Monte Carlo Phase Space Production to Model Magnetically Scanned Proton Beams for IMPT
U Titt1*, D Mirkovic1, L Perles1, M Sell1,2, C Peeler1, A Liu1, R Mohan1, (1) The University of Texas MD Anderson Cancer Center, Houston, TX, (2) German Cancer Research Center (DKFZ), Heidelberg, GermanySU-E-T-474 Sunday 3:00:00 PM - 6:00:00 PM Room: Exhibit Hall
Purpose: Accurate dose predictions in proton beam therapy using magnetically scanned beams are highly dependent on the accurate modeling of the lateral dose profiles. This study was performed to provide proton phase spaces for Monte Carlo simulations, used to accurately simulate doses at distances up to 12 cm from the central axis of the beam.
Methods: Measured lateral dose profiles at various depths in water were compared to Monte Carlo simulations of doses for 90 discreet initial proton energies. Phase spaces were produced using a one dimensional energy distribution, and a combination of several two dimensional spatial and directional distributions. Simulations were performed iteratively using variations in the initial phase space distributions to achieve acceptable agreement between measured and simulated lateral dose profiles, i.e. differences in FWHM < 0.5 mm and dose differences less that 0.1% at distances up to 12.5 cm.
Results: 90 phase spaces of proton sources for different initial beam energies were created for use in Monte Carlo simulations of scanned proton beam therapy patient plans. At a depth of 2 cm in water, the simulated and measured FWHM of the lateral dose profiles differed in in-plane direction by an average of 0.05 mm, in cross-plane direction by 0.13 mm. All simulated profiles were within 0.1% of the measured doses at distances between 2cm and 12.5 cm from the central beam axis.
Conclusions: A library of 90 phase space files has been created to accurately simulate magnetically scanned proton beams for IMPT, providing accurate dose distributions up to 12 cm distance from the central beam axis.