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Control of Respiratory Motion by Hypnosis Intervention During Radiotherapy of Lung Cancer

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R Li

R Li*, Y Xie, S Yu, Y Yang, S Wu, M An, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong

SU-E-J-144 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Purpose:
To effectively control respiratory motion during radiotherapy of lung cancer without any side effects.

Methods:
A novel motion control scheme, hypnosis, has been introduced in lung cancer treatment. As we know, the uncertain position of lung tumor compromises the treatment effect. However, during hypnosis the respiration becomes uniform and stability compared to normal respiration. Therefore, hypnosis can be a helpful technique for respiratory control. Six volunteers are selected with a wide range of distribution of height, weight, and vital capacity. A set of experiments have been conducted for each volunteer, which is guided by a professional hypnotist. The amplitude of respiration has been recorded in the normal state and hypnosis state, respectively. Statistics approaches are used to analysis the data after experiments. All the experiments are repeated twice in the same condition.

Results:
The mean and root-mean-square (RMS) of the breathing amplitude are calculated for each experiment. The stability of the peaks and the similarity of the adjacent wave are also analyzed. The mean and the RMS of the amplitude are 16.2mm and 8.6mm during hypnosis state, while they are 37.4mm and 23.9mm during normal state. It can be seen that the mean and the RMS during hypnosis state are 56.6% and 64.2% smaller than during normal state, respectively. Moreover, the passing ratio of γ index between one of the 13 adjacent cycles and the others during hypnosis state is 16.4% higher than during normal state.

Conclusion:
The hypnosis intervention can be an alternative way for respiratory control, which can effectively reduce the respiratory amplitude and increase the stability of respiratory cycle. It will find useful application in image guided radiotherapy.

Funding Support, Disclosures, and Conflict of Interest: This work is supported in part by grants from National Natural Science Foundation of China (NSFC: 81171402), NSFC Joint Research Fund for Overseas Research Chinese, Hong Kong and Macao Young Scholars (30928030), National Basic Research Program 973 (2010CB732606) from Ministry of Science and Technology of China, and Guangdong Innovative Research Team Program (No. 2011S013) of China.

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