BEST IN PHYSICS (IMAGING) - Strategies for Fluence Field Modulated CT
S Bartolac1,2*, D Jaffray1,2, (1) University of Toronto ,Toronto, ON, (2) Princess Margaret Hospital, Toronto, ONWE-C-103-2 Wednesday 10:30AM - 12:30PM Room: 103
Purpose: Fluence field modulated computed tomography (FFMCT) proposes using dynamically changing fluence fields during image acquisition for advanced dose reduction and image quality optimization. This work compares the relative effectiveness of FFMCT when the modulator is subject to limiting constraints, such as might be introduced by real physical modulators.
Methods: Several tasks were defined for a simulated anthropomorphic chest phantom by defining different regions of high and low image quality, characterized by the signal standard deviation. Optimal modulation fluence patterns were sought for each task using a simulated annealing optimization script, which attempts to achieve the image quality plan under a global dosimetric constraint. Optimization was repeated under different types of modulation constraints representing several different realistic modulator designs (e.g. dynamically varying apertures, discrete fixed apertures, or shaped static filters). Results were compared based on predicted dose outcomes and agreement with the prescribed image quality criteria.
Results: Compared to static modulators (e.g. bowtie filter), fluence field modulation approaches utilizing dynamically changing modulators showed improved agreement with the prescribed outcomes, including greater uniformity of image noise over the target regions of interest. For some tasks, highly constrained modulators approached outcomes similar to that of the ideal unconstrained case. Average integral dose reduction compared to a uniform reference field exceeded 20% for all modulation methods.
Conclusions: The results support that FFMCT can achieve regionally varying image quality distributions in good agreement with user-prescribed values, while reducing dose to the patient. The outcomes also support that the benefits of fluence field modulation may be yielded even when highly constrained modulators are used, suggesting practical, feasible implementations of FFMCT may be possible.
Funding Support, Disclosures, and Conflict of Interest: Research funded in part by the Ontario Graduate Scholarships (OGS), Natural Sciences and Engineering Research Council of Canada (NSERC), Elekta Inc. and the Ontario Research Fund (ORF)
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