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BEST IN PHYSICS (JOINT IMAGING-THERAPY): A Real-Time Tumor Tracking Using Novel Scatter Imaging Modality During Lung SBRT

G Cifter

G Cifter*, G Redler , C Lee , A Templeton , D Bernard , J Turian , J Chu , Y Liao , Rush University Medical Center, Chicago, IL


TH-AB-202-6 (Thursday, August 4, 2016) 7:30 AM - 9:30 AM Room: 202

Purpose:Compared to traditional radiotherapy techniques, stereotactic body radiation therapy (SBRT) provides more favorable outcomes during the treatment of certain lung tumors. Despite advancements in image guidance, accurate target localization still remains a challenge. In this work, we expand our knowledge of a novel scatter imaging modality in order to develop a real-time tumor localization method using scattered photons from the patient during treatment.

Methods:Images of the QUASARâ„¢ Respiratory Motion Phantom were taken by irradiating it on a Varian TrueBeam accelerator. The scattered radiation was detected using a flat panel-based pinhole camera detection system. Two motion settings were investigated: static and dynamic. In the former, the lung tumor was manually shifted between imaging. In the latter, the lung tumor was set to move at a certain frequency and amplitude while the images were acquired continuously for one minute. The accuracy of tumor localization and the irradiation time required to distinguish the lung tumor were studied.

Results:The comparison of measured and expected location of the lung tumor during static motion was shown to be under standard deviation (STD) of 0.064 with a mean STD of 0.031cm. The dynamic motion was taken at a rate of 1400 MU/min for one minute and the measured location of the lung tumor was then compared with the QUASAR phantom’s sinusoidal motion pattern and the agreement found to be at an average STD of 0.275cm. The location of the lung tumor was investigated using aggregate images consisting of 1 or 2 frames/image and the change was below STD of 0.30cm. The lung tumor also appeared to be blurrier in images consisting of two frames.

Conclusion:Based on our preliminary results real-time image guidance using the scatter imaging modality to localize and track tumors during lung SBRT has the potential to become clinical reality.

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