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Niko Papanikolaou

NIKO PAPANIKOLAOU

Profession:
Medical Physicist

Birth:
Greece

Education:
Ph.D. - University of Wisconsin - Madison (Medical Physics 1994)
M.S. - University of Wisconsin - Madison (Medical Physics 1991)
B.S. - University of Athens - Greece (Physics honors 1989)

Certification:
Certificate in Health Care Management - University of Kentucky 1998
Certified Gamma Knife user- Univ. of Pittsburgh Gamma Knife School 2001
Certified - American Board of Radiology in Therapeutic Physics
Radiation expert - State of Kentucky
Licensed Medical physicists in the state of Texas

Fellowships:
University of Wisconsin - Madison

Career:
Dr. Papanikolaou is an active member of several professional organizations, including AAPM, ACMP, ASTRO and ESTRO where he has served in a number of task groups and committees. He has been invited to present in several national and international meetings and he serves as an associate editor for the journals of Medical Physics and the Journal of Applied Clinical Medical Physics.  He has authored and co-authored several papers in the area of radiation oncology and medial physics.  His clinical and research interest include, dose computation algorithms, intensity modulated radiotherapy, optimization and image guided radiotherapy.

Publications:

  1. Mavroidis P, Komisopoulos G, Lind BK, Papanikolaou N.,  “Interpretation of the dosimetric results of three uniformity regularization methods in terms of expected treatment outcome,”  Med. Phys., 35(11), p. 5009-18, Nov 2008.
  2. Sarkar V, Stathakis S, Papanikolaou N., “A Monte Carlo model for independent dose verification in serial tomotherapy,”  Technol Cancer Res Treat., 7(5), p. 385-92, Oct 2008.
  3. Lin L, Shi C, Liu Y, Swanson G, Papanikolaou N., “Development of a novel post-processing treatment planning platform for 4D radiotherapy,”  Technol Cancer Res Treat., 7(2), p. 125-32, Apr 2008.
  4. Mavroidis P, Ferreira BC, Shi C, Lind BK, Papanikolaou N., “Treatment plan comparison between helical tomotherapy and MLC-based IMRT using radiobiological measures,” Phys Med. Biol., 7;52(13), p. 3817-36, Jul 2007. Epub May 31, 2007.
  5. Shi C, Papanikolaou N, Yan Y, Weng X, Jiang H., “Analysis of the sources of uncertainty for EDR2 film-based IMRT quality assurance,”  J Appl Clin Med. Phys., 25;7(2), p. 1-8, May 2006.
  6. Stathakis S, Kappas C, Theodorou K, Papanikolaou N, Rosenwald JC., “An inhomogeneity correction algorithm for irregular fields of high-energy photon beams based on Clarkson integration and the 3D beam subtraction method,” J Appl Clin Med. Phys., 7(1), p. 1-13, Winter 2006. Epub Feb 15, 2006.
  7. Penagaricano J, Papanikolaou N, Youssef E, Wu C, Yan Y, Ratanatharathorn V., “Intensity-modulated radiation therapy (IMRT) enabling technologies,” J Ark Med. Soc., 102(4), p. 114-7, Oct 2005. No abstract available.
  8. Yan Y, Papanikolaou N, Weng X, Penagaricano J, Ratanatharathorn V., “Fast radiographic film calibration procedure for helical tomotherapy intensity modulated radiation therapy dose verification,” Med. Phys., 32(6), p. 1566-70, Jun 2005.
  9. Peñagarícano JA, Papanikolaou N, Yan Y, Youssef E, Ratanatharathorn V., “Feasibility of cranio-spinal axis radiation with the Hi-Art tomotherapy system,” Radiother Oncol., 76(1), p. 72-8, Jul 2005.
  10. Peñagarícano JA, Papanikolaou N, Wu C, Yan Y., “An assessment of biologically-based optimization (BORT) in the IMRT era,” Med. Dosim., 30(1), p. 12-9, Spring 2005.
  11. Reft C, Alecu R, Das IJ, Gerbi BJ, Keall P, Lief E, Mijnheer BJ, Papanikolaou N, Sibata C, Van Dyk J., “Dosimetric considerations for patients with HIP prostheses undergoing pelvic irradiation. Report of the AAPM Radiation Therapy Committee Task Group 63,” Med. Phys., 30(6), p. 1162-82, Jun 2003.
  12. Salter BJ, Fuss M, Sarkar V, Wang B, Rassiah-Szegedi P, Papanikolaou N, Hollingshaus S, Shrieve DC., “Optimization of isocenter location for intensity modulated stereotactic treatment of small intracranial targets,” Int J Radiat Oncol Biol Phys., 73(2), p. 546-55, Feb 1, 2009.
  13. Liu Y, Shi C, Tynan P, Papanikolaou N., “Dosimetric characteristics of dual-layer multileaf collimation for small-field and intensity-modulated radiation therapy applications,” J Appl Clin Med. Phys., 9(2), p. 2709, Mar 31, 2008.
  14. Shi C, Peñagarícano J, Papanikolaou N., “Comparison of IMRT treatment plans between linac and helical tomotherapy based on integral dose and inhomogeneity index,” Med. Dosim., 33(3), p. 215-21, 2008 Autumn. Epub Apr 7, 2008.
  15. Siddiqui F, Shi C, Papanikolaou N,Fuss M., “Image-guidance protocol comparison: supine and prone set-up accuracy for pelvic radiation therapy,” Acta Oncol., 47(7), p. 1344-50, 2008.
  16. Su FC, Shi C, Crownover R, Swanson G, Papanikolaou N., “Dosimetric impacts of gantry angle misalignment on prostate cancer treatment using helical tomotherapy,” Technol Cancer Res Treat., 7(4), p. 287-93, Aug 2008.
  17. Roland TF, Stathakis S, Ramer R, Papanikolaou N., “Measurement and comparison of skin dose for prostate and head-and-neck patients treated on various IMRT delivery systems,” Appl Radiat Isot., 66(12), p. 1844-9, Dec 2008. Epub May 17, 2008.
  18. Su FC, Shi C, Papanikolaou N., “Clinical application of GAFCHROMIC EBT film for in vivo dose measurements of total body irradiation radiotherapy,” Appl Radiat Isot., 66(3), p. 389-94, Mar 2008. Epub Oct 10, 2007.
  19. Sarkar V, Lin L, Shi C, Papanikolaou N., “Quality assurance of the multileaf collimator with helical tomotherapy: design and implementation,” Med. Phys., 34(7), p. 2949-56, Jul 2007.
  20. Su FC, Liu Y, Stathakis S, Shi C, Esquivel C, Papanikolaou N., “Dosimetry characteristics of GAFCHROMIC EBT film responding to therapeutic electron beams,” Appl Radiat Isot., 65(10), p. 1187-92, Oct 2007. Epub May 29, 2007.
  21. Rassiah-Szegedi P, Salter BJ, Fuller CD, Blough M, Papanikolaou N, Fuss M., “Monte Carlo characterization of target doses in stereotactic body radiation therapy (SBRT),” Acta Oncol., 45(7), p. 989-94, 2006.
  22. Fuss M, Shi C, Papanikolaou N., “Tomotherapeutic stereotactic body radiation therapy: Techniques and comparison between modalities,” Acta Oncol., 45(7), p. 953-60, 2006.
  23. Joyner M, Salter BJ, Papanikolaou N, Fuss M., “Stereotactic body radiation therapy for centrally located lung lesions,” Acta Oncol., 45(7), p. 802-7, 2006.
  24. Peñagarícano JA, Ratanatharathorn V, Papanikolaou N, Yan Y., “Intensity-modulated radiation therapy reduces the dose to normal tissue in T2N0M0 squamous cell carcinoma of the glottic larynx,” Med. Dosim., 29(4), p. 254-7, Winter 2004.
  25. Peñagarícano JA, Papanikolaou N, Yan Y, Ratanatharathorn V., “Application of intensity-modulated radiation therapy for pediatric malignancies,” Med. Dosim., 29(4), p. 247-53, Winter 2004.
  26. Peñagarícano JA, Papanikolaou N., “Intensity-modulated radiotherapy for carcinoma of the head and neck,” Curr Oncol Rep., 5(2), p. 131-9, Mar 2003
  27. Papanikolaou N, Mackie, TR., “A new convolution approach for the generation of polyenergetic photon beam dose distributions,” Med. Phys., 19(3), p. 821, 1992
  28. Mackie TR, Reckwerdt P, Holmes T, Papanikolaou N, Simpkin D. “The concept of secondary radiation equilibrium," Med. Phys., 19(3), p. 785, 1992.
  29. Meger-Wells CM, Mackie TM, Podgorsak MB, Papanikolaou N, Holmes M, Reckwerdt P, Attix FH.  “Electron dose distribution measurements in inhomogeneous phantoms using a plastic scintillation detector," Med. Phys., 19(3), p. 840, 1992.
  30. Papanikolaou N, Mackie TR, Wells C, Gehring M, Reckwerdt P.  “Investigation of the convolution method for polyenergetic spectra,” Med. Phys., 20(5), pp. 1327-1336, 1993
  31. Papanikolaou N, Mackie TR.  “Generation of photon convolution kernels using a Monte Carlo   Code for use in radiotherapy treatment planning and cavity theory," Med. Phys., 20(3), p. 901, 1993.
  32. N. Papanikolaou, B. Paliwal,  “A Monte Carlo study of the dosimetric characteristics of intraoperative radiotherapy cones," Med. Phys., 20(3), p. 900, 1993.
  33. Meger-Wells CM, Mackie TR, Papanikolaou N, Frye DMD, “Dosimetry of Stereotactic Radiosurgery Beams Using a Plastic Scintillation Detector,” Med. Phys., 20(3), 1993
  34. Papanikolaou N, Mackie TR,  “Separation of photon beam output factor into its phantom and machine generated components using a convolution code,”  Med. Phys., 21(6),  p. 877, 1994.
  35. Papanikolaou N, Mackie TR. "The extended phantom concept: modeling the treatment machine modifiers and portal imaging dosimetry system using a convolution code,” Med. Phys., 21(6), p. 877, 1994
  36. Papanikolaou N, Mackie TR. “Extension of the convolution/superposition based algorithms to include atomic number effects,” Med. Phys., 22(6), p. 977, 1995.
  37. Papanikolaou N, Paliwal B.  “A study of the effect of cone shielding in intraoperative radiotherapy,” Med. Phys., 22(5), pp. 571-575, 1995
  38. McNutt T, Mackie TR, Reckwerdt P, Papanikolaou N, Paliwal B.  “Modeling portal dose using the convolution/ superposition method," Med. Phys., 22(6) p. 992, 1995.

American Association of Physicists in Medicine Activities:
AAPM – member since 1990
                  Computers Committee 1999-2001
                  European Affairs Subcommittee since 2001-2004
                  Imaging for Treatment Verification Work Group since 2007-2009
                  Molecular Imaging in Radiation Oncology Work Group since 2007-2009
                  Professional Information and Clinical Relations since 1999-2001
                  Task Group No. 65 (Tissue Inhomogeneity Corrections for Photon Beams)-Chair
                  Task Group No. 148 (QA for Helical Tomotherapy) -Chair
                  Task Group No. 63 (Management of Radiation Oncology Patients with Implanted
                        High Z Materials)
                  Work Group on Coordination of Medical Physics Residency Programs since
                        2006-2008
                  Work Group on Radiation Dosimetry since 2005
                  Work Group on Recommendations for Radiotherapy External Beam Quality
                        Assurance since 2006

Other Professional Organization Activities:
ACMP – member since 1999
                  Treasurer since 2008
                  Executive Committee since 2008
                  Board of Chancellors since 2008
                  Meeting Location Committee since 2009
                  Membership Committee since 2009
                  Meeting Program Committee since 2008
                  Meeting Task Group since 2008
                  Strategic Planning Committee since 2008
                  Journal of Applied Clinical Medical Physics since 2006
                  Finance Committee since 2007 
                  Planning TG of the Meeting Program since 2007
                  Commission on Communications member since 2006
                  Therapy Standards Subcommittee member since 2004
ASTRO – member since 1992
ESTRO – member since 1992
ACR –  member since 1996
ABR –  Written exam committee since 2004
Oral Examiner since 2006
Journal of Applied Clinical Medical Physics – Associate Editor
Medical Physics Journal – Associate Editor
Journal of Nuclear Medicine – Reviewer
Physics in Medicine and Biology – Reviewer
International Journal of Radiation Oncology Biology Physics – Reviewer

Family:

wife-Tomi Papanikolaou, children-Alexander, Katerina, Nikolas, Rebeka