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CHARLES E. METZEdward Lee Nickoloff


Profession: Medical Physicist

Birth: September 11, 1942

Education:
1964    B.A. cum laude (Physics), Bowdoin College
1966    M.S.  (Radiological Physics), University of Pennsylvania
1969    Ph.D. (Radiological Physics), University of Pennsylvania

Career:
After joining the Department of Radiology at The University of Chicago as Instructor in 1969, Dr. Metz was promoted to Assistant Professor in 1971, to Associate Professor in 1976 and to Professor in 1980.  His research interests include various applications of signal detection theory and systems analysis in medical imaging, with emphasis on image reconstruction from projections and the development of receiver operating characteristic (ROC) methodology for quantitative evaluation of diagnostic performance.  Dr. Metz is the author or a co-author of more than 250 scientific publications, and ROC software developed by his group is now used by more than 10,000 laboratories around the world.  In 1995 Dr. Metz received the first annual Kurt Rossmann Award for Excellence in Teaching by vote of students in The University of Chicago's Graduate Programs in Medical Physics (now Committee on Medical Physics).  He was elected as a Fellow of The American Association of Physicists in Medicine in 2004, received the Paul C. Hodges Alumni Society's Excellence Award in November 2004, and was awarded the 12th L.H. Gray Medal by the International Commission on Radiation Units and Measurements in 2005.  Dr. Metz's biography is included in a variety of published listings, including Marquis Who's Who in America and Marquis Who's Who in the World.

Publications [Up to 15]:
Metz CE.  Basic principles of ROC analysis.  Seminars in Nuclear Medicine 8: 283-298, 1978.

Metz CE, Doi K.  Transfer function analysis of radiographic imaging systems.  Physics in Medicine & Biology 24: 1079-1106, 1979.

Tretiak O, Metz CE.  The exponential Radon transform.  SIAM Journal of Applied Mathematics 39: 341-357, 1980.
Metz CE.  ROC methodology in radiologic imaging.  Investigative Radiology 21: 720-733, 1986.

Metz CE.  Some practical issues of experimental design and data analysis in radiological ROC studies. Investigative Radiology 24: 234-245, 1989.

Dorfman DD, Berbaum KS, Metz CE.  Receiver operating characteristic rating analysis: generalization to the population of readers and patients with the jackknife method.  Investigative Radiology 27: 723-731, 1992.

Metz CE, Shen J-H.  Gains in accuracy from replicated readings of diagnostic images: prediction and assessment in terms of ROC analysis.  Medical Decision Making 12: 60-75, 1992.

Metz CE, Pan X.  A unified analysis of exact methods of inverting the 2-D exponential Radon transform.  IEEE Transactions on Medical Imaging 14: 643-658, 1995.

Roe CA, Metz CE.  Variance-component modeling in the analysis of ROC index estimates.  Academic Radiology 4: 587-600, 1997.

Metz CE, Herman BA, Shen J-H.  Maximum-likelihood estimation of ROC curves from continuously-distributed data.  Statistics in Medicine 17: 1033-1053, 1998.

Metz CE, Pan X.  “Proper” binormal ROC curves: theory and maximum-likelihood estimation.  Journal of Mathematical Psychology 43: 1-33, 1999.

Wagner RF, Beiden SV, Metz CE.  Continuous vs. categorical data for ROC analysis: Some quantitative considerations.  Academic Radiology 8: 328-334, 2001.

Wagner RF, Beiden SV, Campbell G, Metz CE, Sachs WM.  Assessment of medical imaging and computer-assist systems: lessons from recent experience. Academic Radiology 8: 1264-1277, 2002.

Edwards DC, Metz CE, Kupinski MA.  Ideal observers and optimal ROC hypersurfaces in N-class classification. IEEE Transactions on Medical Imaging 23: 891-895, 2004.

Wagner, RF, Metz, CE, Campbell, G.  Assessment of medical imaging system and computer aids: a tutorial review. Academic Radiology 14: 723-748, 2007.

Awards:
1995    First annual Kurt Rossmann Award for Excellence in Teaching: Graduate Programs in Medical Physics, Departments of Radiology and Radiation & Cellular Oncology, The University of Chicago
2004    Excellence Award, Paul C. Hodges Alumni Society, Department of Radiology, The University of Chicago
2005    Twelfth L.H. Gray Medal, International Commission on Radiation Units and Measurements

American Association of Physicists in Medicine (AAPM) Activities:
1973 - 1976     Member, Committee on Training of Medical Physicists
1975 - 1978     Member, Scientific Program Committee
1992 - 1995     Associate Editor, Medical Physics

Other Professional Organization Activities: