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Charles A. MistrettaCHARLES A. MISTRETTA

Occupation: Medical physicist specializing in MRI and X-Ray CT
Born: Jan 5 1941

Education:
BS Engineering Physics University of Illinois Champaign Urbana 1962
MS Physics Harvard University 1964
PhD High Energy Physics Harvard University 198

Certifications:
None

Postdoctoral Positions
1968-70 Research Associate, Dept. of Physics, U. of Wisconsin
1970-71 Lecturer, Dept. of Physics, U. of Wisconsin

Faculty Positions
1971-72 Assist. Prof., Depts. of Physics & Radiology, U.W. Madison
1974-78 Assoc. Prof., Dept. of Radiology, Medical Physics Section, U.W. Madison
1978-82 Professor, Dept. of Radiology, Medical Physics Section, U.W. Madison
1982-85 Professor, Depts. of Radiology and Medical Physics, U.W. Madison
1985-86 WARF Prof., Depts. of Radiology and Medical Physics, U.W. Madison
1986-present John R. Cameron Professor, Depts. of Medical Physics and Radiology, U.W.
2000-present Faculty Affiliate, Department of Biomedical Engineering, U.W.

Mentoring 29 PhD students, 22 Post doctoral fellows. Examples and areas of activity include; Willi Kalender, Primary developer of Spiral CT, Robert Kruger, Co-inventor of Digital Subtraction Angiography and Thermoacoustic CT, Stephen Riederer, Inventor of MR Fluoroscopy and fast MRI methods, Orhan Nalcioglu, Contrast enhanced MRI methods for breast cancer, Bruce Hasegawa, Dual modality SPECT/CT imaging, James Dobbins, Dual energy tomosynthesic chest radiography,Yi Wang, Fast vascular MRI methods.

Research Areas : K-edge subtraction imaging, digital subtraction angiography, dual energy digital chest radiography, x-ray capillary optics, applications of DSA to measurement of coronary flow reserve, x-ray beam compensation techniques, MRI flow measurement, time resolved 3D MR angiography, ultrafast MRI imaging using vastly undersampled 3D projection acquisition (VIPR). Extension of VIPR to X-ray CT.

Patents 23 patents and several pending applications.

Publications [Up to 15]:

  1. The use of a general description of the radiological transmission image for categorizing imaging enhancement procedures. Optical Engineering 13(2):134, 1974.

  2. 2 Kelcz F, Mistretta CA: Absorption edge fluoroscopy using a 3-spectrum technique. Medical Physics 3(3):159-168, 1977.

  3. Kruger RA, Mistretta CA, Crummy AB, Sackett JF, Goodsit MM, Riederer SJ, Houk TL, Shaw CG, Flemming D: Digital k-edge subtraction radiography. Radiology 125:234-235, 1977.

  4. Kruger RA, Mistretta CA, Riederer SJ, Ergun DL, Shaw CG, Rowe GG: Computerized fluoroscopy techniques for noninvasive imaging of the cardiovascular system. Radiology 130(1): 49-57, 1979.

  5. Van Lysel MS, Dobbins JT III, Peppler WW, Hasegawa BH, Lee CS, Mistretta CA, Zarnstorff WC, Crummy AB, Kubal W, Bergsjordet B, Strother CM, Sackett JF: Work in progress: Hybrid temporal-energy subtraction in digital fluoroscopy. Radiology 147(3):869-874, 1983.

  6. Hasegawa BH, Naimuddin S, Dobbins JT III, Mistretta CA, Peppler WW, Hangiandreou NJ, Cusma JT, McDermott J, Kudva B, Melbye K: Digital beam attenuator technique for compensated chest radiography. Radiology 159:537-543, 1986.

  7. Van Lysel MS, Ergun DL, Miller WP, Toggart EJ, Cusma JT, Peppler WW, Molloi SY, Mistretta CA: Cardiac digital angiography and dual-energy subtraction imaging: Current and future trends. Amer J Cardiac Imaging, 1:254-256, 1987.

  8. Cusma JT, Toggart EJ, Folts JD, Peppler WW, Hangiandreou NJ, Lee CS, Mistretta CA: DSA imaging of coronary flow reserve. Circulation 75(2):461-472, 1987.

  9. Wang Y, Mistretta CA, Shefer R, Manning H: Considerations regarding the use of x-ray capillary optics in medical radiography. Medical Physics, 19(3):533-544, May/June 1992.

  10. Wang Y, Christy PS, Korosec MR, Alley MT, Grist TM, Polzin JA, Mistretta CA: Coronary MRI with a respiratory feedback monitor: The 2D imaging case. Magnetic Resonance in Medicine 33:116-121, 1995.

  11. Polzin JA, Alley MT, korosec FR, Grist TM, Wang Y, Mistretta CA: A complex difference phase-contrast technique for measurement of volume flow rates. Journal of Magnetic Resonance Imaging,5:129-137,1995.

  12. FR Korosec, R Frayne, TM Grist, and CA Mistretta, Time-Resolved Contrast-Enhanced 3D MR Angiography, Magn. Reson. Med 36:345-351(1996)

  13. Dana C. Peters, Thomas M. Grist, Frank R. Korosec, James E. Holden, Walter F. Block, Kristin L. Wedding, Timothy J. Carroll, Charles A. Mistretta, Undersampled Projection Reconstruction Applied to MR Angiography, Magn. Reson. Med., 43(1) 91-101 (2000).

  14. AV. Barger, W F. Block, Yuriy Toropov, TM. Grist, CA. Mistretta, Time-Resolved Contrast-Enhanced Imaging with Isotropic Resolution and Broad Coverage Using an Undersampled 3D Projection Trajectory, Magn Reson Med ., 48, 297-305,2002.

  15. J Du et al. , High Resolution Multistation Peripheral Angiography Using Undersampled Projection Reconstruction Imaging, Magnetic Resonance in Medicine, Vol 52, No.1,204-208 July 2004.

Awards:

1972-74 First physicist to become James Picker Advanced Fellow in Academic Radiology,

1983 Laufman-Greatbatch Prize, Association for the Advancement of Medical Instrumentation, in recognition for development of Digital Subtraction Angiography (DSA)

1998 J. Allyn Taylor International Prize in Medicine, sponsored by the Robarts Research Institute and the University of Western Ontario, for “distinguished lifetime achievement” and “outstanding contributions to the advances in the use of medical imaging in diagnosing and treating human diseases”.

1999 Elected Fellow of the American Association of Physicists in Medicine.

2003 Elected Fellow of American Institute for Medical and Biological Engineering

American Association of Physicists in Medicine (AAPM) Activities:

Summer School Faculty
Survey of Medial Physics training programs
Scientific Session Chairmanships
Invited scientific presentations
Medical Physics manuscript Reviews

Additional Professional Organization Activities:

International Society for Magnetic Resonance in Medicine
American Institute for Medical and Biological Engineering

Civic Activities:

Religious Education Program-Initiation of Program and High School teaching, St. Paul’s University Catholic Center, Madison, WI.
Mission trips to Guatemala and Nicaragua in association with Arms of Jesus, El Porvenir and Agua Para La Vida

Avocations and Special Interests:

Golfing, Fishing, Piano, Video Production

Family: Wife Darlene, married 43 years. Daughters Lauri and Kim. Son Scott. 5 grandchildren.