2016 AAPM Annual Meeting
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Session Title: PET for Radiation Therapy
Question 1: Which of the following PET radiotracers is a hypoxia imaging agent?
Reference:Carlin S, Humm JL, PET of Hypoxia: Current and Future Perspectives. J Nucl Med. 2012 Aug;53(8):1171-4. PMID: 22789676.
Choice A:Fluorothymidine (FLT)
Choice B:Fluoromisonidazole (FMISO)
Choice C:Fluordeoxyglucose (FDG)
Choice D:Fluoroestradiol (FES)
Choice E:Fluoride (NaF)
Question 2: When measuring the activity of a PET acquisition performed with a hypoxia radiotracer, the voxel intensities within hypoxic tumors relative to background muscle tissue is typically?
Reference:Carlin S, Humm JL, PET of Hypoxia: Current and Future Perspectives. J Nucl Med. 2012 Aug;53(8):1171-4. PMID: 22789676.
Choice A:Less than 1.
Choice B:Between 1 and 3.
Choice C:Between 3 and 10.
Choice D:Greater than 10.
Question 3: What are the advantages of metabolic response assessment by FDG PET/CT compared to anatomic response assessment?
Reference:1 R. L. Wahl, Jacene, H. Kasamon, Y., Lodge, M. A., "From RECIST to PERCIST: Evolving Considerations for PET response criteria in solid tumors.," J Nucl Med. 50 122S-150S (2009).
Choice A:Metabolic change often occurs earlier than anatomic change.
Choice B:Metabolic change is often more substantial than anatomic change.
Choice C:There exists strong correlation between FDG uptake and cancer cell number.
Choice D:FDG PET/CT allows quantitative assessments .
Choice E:All of the above.
Question 4: In computerized PET analysis or radiomics studies, which type of PET image features was found most prominent for tumor response assessment?
Reference:2 W. Lu, J. Wang, and H. H. Zhang, "Computerized PET/CT Image Analysis in the Evaluation of Tumor Response to Therapy," The British Journal of Radiology. 20140625 (2015).
Choice A:Maximal SUV.
Choice B:Metabolic tumor volume.
Choice C:Heterogeneity in tumor uptake.
Choice D:Total lesion glycolysis.
Question 5: The standardized update value measured in PET is not dependent on
Reference:Huang, S.C., Anatomy of SUV. Standardized uptake value. Nucl Med Biol, 2000. 27(7): p. 643-6.
Choice A:Patient height.
Choice B:Patient weight.
Choice C:Injected activity (Bq).
Choice D:Measured activity concentration (KBq/ml).
Choice E:Calibration of the PET system.
Question 6: Which one is not correct for average CT?
Reference:Pan, T., et al., Attenuation correction of PET images with respiration-averaged CT images in PET/CT. J Nucl Med, 2005. 46(9): p. 1481-7.
Choice A:It has a temporal resolution of about one breath cycle.
Choice B:It can be used for dose calculation in RT.
Choice C:It can be used in registration with CBCT in IGRT.
Choice D:It can be derived from 4DCT.
Choice E:It has a well-defined boundary for a moving object.
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