| Question 1: NIH defines a clinical trial as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes. |
| Reference: | https://grants.nih.gov/policy/clinical-trials.htm |
| Choice A: | True |
| Choice B: | False |
| Question 2: NIH requires that all applications involving one or more independent clinical trials be submitted through a Funding Opportunity Announcement (FOA) specifically designated as ‘Clinical Trial Required’ or ‘Clinical Trial Not Allowed’. |
| Reference: | https://grants.nih.gov/policy/clinical-trials/review-criteria.htm |
| Choice A: | True |
| Choice B: | False |
| Question 3: What is the difference if any in cost limit and time duration between an R01 and R03 grant mechanism at NIH? |
| Reference: | https://grants.nih.gov/grants/funding/funding_program.htm#RSeries |
| Choice A: | RO1 is higher in cost allocation limit and longer in time duration than RO3 |
| Choice B: | RO1 is lower in cost allocation limit and shorter in time duration than RO3 |
| Choice C: | RO1 is lower in cost allocation limit and has the same time duration as RO3 |
| Choice D: | Both have same cost limit and time duration, RO3 only covers training grants |
| Question 4: You have an innovative idea, which you believe would be a game-changer. But you don’t have much preliminary data and would really need to fully explore and develop this breakthrough approach, which will have high clinical impact. Which grant mechanism would you focus on? |
| Reference: | https://grants.nih.gov/grants/funding/funding_program.htm#RSeries |
| Choice A: | R01 |
| Choice B: | P01 |
| Choice C: | U01 |
| Choice D: | R21 |
| Question 5: What is the approximate distribution of NIH funding in Radiation Oncology |
| Reference: | Steinberg et al., Int J Radiat Oncol Biol Phys. 2013 Jun 1;86(2):234-40 |
| Choice A: | Radiobiology – 40%, Physics – 30%, Clinical Investigations – 30% |
| Choice B: | Radiobiology – 20%, Physics – 60%, Clinical Investigations – 20% |
| Choice C: | Radiobiology – 80%, Physics – 13%, Clinical Investigations – 7% |
| Choice D: | Radiobiology – 90%, Physics – 7%, Clinical Investigations – 3% |
| Question 6: When should you formulate your budget and justification? |
| Reference: | https://grants.nih.gov/policy/clinical-trials.htm |
| Choice A: | Before or while formulating your Specific Aims |
| Choice B: | After finalizing your Specific Aims |
| Choice C: | After you finish writing the Statistics section |
| Choice D: | Towards the end, after you have finished all other components – Research Plan, Letters, Biosketches, etc. |
| Question 7: What is the most important component of a successful NIH grant |
| Reference: | https://grants.nih.gov/policy/clinical-trials.htm |
| Choice A: | Significance |
| Choice B: | Innovation |
| Choice C: | Investigators |
| Choice D: | Research strategy |
| Question 8: What type of routine reporting is/are required for the National Institutes of Health (NIH) for awarded grants including a patient clinical trial? |
| Reference: | https://grants.nih.gov/grants/post-award-monitoring-and-reporting.htm; |
| Choice A: | Progress reports |
| Choice B: | Institutional Review Board approval documentation |
| Choice C: | Financial reports |
| Choice D: | Subaward reports |
| Choice E: | All of the above |
| Question 9: The Principal Investigator must provide an explanation and indicate plans for expenditure of allocated funds when the unobligated grant balance is greater than what percentage? |
| Reference: | https://grants.nih.gov/grants/policy/nihgps/html5/section_8/8.1_changes_in_project_and_budget.htm |
| Choice A: | 5% |
| Choice B: | 10% |
| Choice C: | 25% |
| Choice D: | 50% |
| Question 10: The National Institutes of Health requires NIH-funded investigators to submit an electronic version of their accepted peer-reviewed manuscripts within 12 months of publication to which website? |
| Reference: | https://publicaccess.nih.gov/policy.htm |
| Choice A: | Google Scholar |
| Choice B: | LinkedIn |
| Choice C: | Individual institution websites |
| Choice D: | National Library of Medicine’s PubMed Central |
