2018 AAPM Annual Meeting
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Session Title: Statistical Failings: The Shadow Still Hiding Clinical Truth
Question 1: The process of cherry-picking promising findings and thereby risking spurious statistically-significant results is sometimes called:
Reference:R.L. Wasserstein and N.A. Lazar, The ASA’s statement on p-values, context, process, and purpose, The American Statistician, accepted version published online 3/7/2016.
Choice A:Data dredging.
Choice B:P-hacking.
Choice C:Significance chasing.
Choice D:Selective inference.
Choice E:All of the above.
Question 2: A p-value can best be described as the probability, under a specified statistical model, that ______________.
Reference:Reference: R.L. Wasserstein and N.A. Lazar, The ASA’s statement on p-values, context, process, and purpose, The American Statistician, accepted version published online 3/7/2016.
Choice A:The null hypothesis is true.
Choice B:A statistical summary of the data would be equal to or more extreme than its observed value.
Choice C:The statistical summary of the data was a random coincidence unique to the given data under analysis.
Choice D:The results would not hold up if the experiment is repeated.
Choice E:The data has sufficient statistical power to detect a given effect.
Question 3: True or false: Bayes theorem provides a method for computing the probability that a hypothesis is true given some observed data or event.
Reference:M. E. J. Masson, “A tutorial on a practical Bayesian alternative to null-hypothesis significance testing”, Behavioral Research 43, 2011.
Choice A:True.
Choice B:False.
Question 4: When describing how a dataset deviates from a normal distribution, kurtosis is a measure of:
Reference:A. Fields et al., Discovering Statistics Using R, Sage, 2012.
Choice A:The sharpness of the peak of the frequency distribution of the dataset.
Choice B:The asymmetry of the frequency distribution of the dataset.
Choice C:The fraction of missing data in the dataset.
Choice D:The area under the frequency distribution curve of the dataset.
Choice E:None of the above.
Question 5: True or False: The Mann-Whitney test and the Wilcoxon’s rank-sum test are non-parametric equivalents of the independent t-test.
Reference:A. Fields et al., Discovering Statistics Using R, Sage, 2012.
Choice A:True.
Choice B:False.
Question 6: In simple linear regression, what is the x-axis variable?
Reference:Agresti, A. An introduction to categorical data analysis 2nd ed. John Wiley & Sons, Hoboken, NJ, 2007.
Choice A:Response variable.
Choice B:Outcome variable.
Choice C:Independent variable.
Choice D:Deterministic variable.
Question 7: The Coefficient of Determination conveys what portion of data variation is accounted for by the model.
Reference:Agresti, A. An introduction to categorical data analysis 2nd ed. John Wiley & Sons, Hoboken, NJ, 2007.
Choice A:True.
Choice B:False.
Question 8: What type of logistic regression is used when the categories have no natural ordering?
Reference:Reference: Agresti, A. An introduction to categorical data analysis 2nded. John Wiley & Sons, Hoboken, NJ, 2007.
Choice A:Binary.
Choice B:Nominal.
Choice C:Ordinal.
Question 9: True or False: The ½ standard deviation method is an accepted criterion for determining clinical significance in quality of life (QOL) studies.
Reference:J. Sloan, et al., “Clinical significance of patient-reported questionnaire data: another step towards consensus”, J. Clinical Epidemiology 58, 2005.
Choice A:True.
Choice B:False.
Question 10: True or False: The Bonferroni correction is the most appropriate method by which to address multiple hypotheses testing in large-scale radiomics projects.
Reference:A. Kumar, et al., “Radiomics: the process and the challenges”, Magnetic Resonance Imaging 30, 2012.
Choice A:True.
Choice B:False.
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