| Question 1: Anatomical changes which may vary highly day to day and which vary highly within the typical time course of a single fraction (minutes to hours) are best managed with which type of adaptive radiation therapy workflow? |
| Reference: | Keall, Paul, Per Poulsen, and Jeremy T. Booth. "See, think, and act: real-time adaptive radiotherapy." Seminars in radiation oncology. Vol. 29. No. 3. 2019. |
| Choice A: | Offline |
| Choice B: | Online |
| Choice C: | Realtime |
| Choice D: | Any of A, B, or C are appropriate |
| Question 2: Which of the following most appropriately lists the set of core enabling technologies of online adaptive radiation therapy? |
| Reference: | Green, Olga L., Lauren E. Henke, and Geoffrey D. Hugo. "Practical clinical workflows for online and offline adaptive radiation therapy." Seminars in radiation oncology. Vol. 29. No. 3. 2019. |
| Choice A: | Anatomical imaging, Functional imaging, Replanning tools |
| Choice B: | Anatomical imaging, Decision support tools, Replanning tools |
| Choice C: | PET, MRI, CT |
| Choice D: | Anatomical imaging, Deformable image registration, Replanning tools |
| Question 3: True or False: Functional adaption can be applied to both target and normal tissues. |
| Reference: | Matuszak MM, Kashani R, Green M, Owen D, Jolly S, Mierzwa M, Functional Adaptation in Radiation Therapy, Seminars in Radiation Oncology 2019, 29 (3), Pages 236-244. |
| Choice A: | True |
| Choice B: | False |
| Question 4: Which of the following is the most clear example of a functional adaptation in radiation therapy? |
| Reference: | Matuszak MM, Kashani R, Green M, Owen D, Jolly S, Mierzwa M, Functional Adaptation in Radiation Therapy, Seminars in Radiation Oncology 2019, 29 (3), Pages 236-244 |
| Choice A: | Obtaining pre-treatment PET imaging |
| Choice B: | Minimizing mean dose to normal lung in treatment planning |
| Choice C: | Changing a prostate plan mid-treatment due to differences in bladder filling |
| Choice D: | Updating the tumor prescription based on the difference between mid- and pre-treatment diffusion weighted MRI in head/neck |
| Question 5: Failure mode and effects analysis (FMEA) indicates that offline adaptive radiotherapy: |
| Reference: | Noel CE, Santanam L, Parikh PJ, Mutic S. Process-based quality management for clinical implementation of adaptive radiotherapy. Med Phys. 2014;41 (8Part1):081717. |
| Choice A: | has lower risk priority numbers (PRN) than the standard planning |
| Choice B: | introduces unique new critical failures |
| Choice C: | has the same critical failures as the standard planning |
| Choice D: | has equal risk priority numbers as the standard planning |
| Question 6: Which of the following are the key components of the workflow of adaptive radiotherapy |
| Reference: | Green OL, Henke LE, Hugo GD. Practical Clinical Workflows for Online and Offline Adaptive Radiation Therapy. Semin Radiat Oncol. 2019 Jul;29(3):219–27. |
| Choice A: | imaging for monitoring |
| Choice B: | assessment |
| Choice C: | re-planning |
| Choice D: | quality assurance |
| Choice E: | all of above |
