| Question 1: Which of the following statements is INCORRECT? |
| Reference: | Leidholdt, E. M., Seibert, J. A., Bushberg, J. T., Boone, J. M. (2002). The Essential Physics of Medical Imaging. United Kingdom: Lippincott Williams & Wilkins. |
| Choice A: | Relative contrast in T1, T2 weighted images depends on pulse sequences |
| Choice B: | Relative contrast in T1, T2 weighted images depends on inherent tissues T1, T2 values |
| Choice C: | T1, T2 weighted images are routinely used in the clinic for tumor delineation |
| Choice D: | DWI imaging is just another form of T1, T2 weighted imaging |
| Question 2: Which of the following statements is INCORRECT? Diffusion weighted imaging: |
| Reference: | R Bammer, Basic Principles of Diffusion-Weighted Imaging, Eur J Radiol. 2003 Mar;45(3):169-84. doi: 10.1016/s0720-048x(02)00303-0. |
| Choice A: | Primarily measures the water molecular motion in tissue |
| Choice B: | is a NOT a measure of the respiratory motion |
| Choice C: | does not need QA because DWI is quantitative already |
| Choice D: | in tumor response to radiation, diffusion should increase |
| Question 3: Prostate Imaging - Reporting and Data System Version 2 (PI-RADS™ v2) provides recommendations on prostate diagnosis using multi-parametric MRI. What MRI field strengths does this document recommend using for prostate mpMRI? |
| Reference: | Weinreb, J.C., Barentsz, J.O., Choyke, P.L., Cornud, F., Haider, M.A., Macura, K.J., Margolis, D., Schnall, M.D., Shtern, F., Tempany, C.M. and Thoeny, H.C., 2016. PI-RADS prostate imaging–reporting and data system: 2015, version 2. European urology, 69(1), pp.16-40. |
| Choice A: | 3 Tesla |
| Choice B: | 1.5 Tesla |
| Choice C: | Greater than or equal to 1.5 Tesla |
| Choice D: | Less than 1.5 Tesla |
| Question 4: Which of the following statements is INCORRECT about multi-parametric MRI? |
| Reference: | Kumar V, Bora GS, Kumar R, Jagannathan NR. Multiparametric (mp) MRI of prostate cancer. Prog Nucl Magn Reson Spectrosc. 2018;105:23-40. |
| Choice A: | Uses same sequences for different anatomical sites |
| Choice B: | Provides more accurate tumor assessment than conventional MRI |
| Choice C: | Brings challenges of analyzing and displaying large amount of data |
| Choice D: | Provides improved reproducibility and reliability than conventional MRI |
| Question 5: Which type of MR image is UNLIKELY to be acquired in simultaneous multi-parametric MRI? |
| Reference: | Amthor T, Doneva M, Koken P, Sommer K, Meineke J, Bornert P. Magnetic Resonance Fingerprinting with short relaxation intervals. Magn Reson Imaging. 2017;41:22-28. |
| Choice A: | T1-weighted |
| Choice B: | T2-weighted |
| Choice C: | Proton density weighted |
| Choice D: | Dynamic contrast enhanced |
| Question 6: Which one of the following is UNLIKELY to be a radiotherapy application for multi-parametric MRI? |
| Reference: | Citak-Er F, Firat Z, Kovanlikaya I, Ture U, Ozturk-Isik E. Machine-learning in grading of gliomas based on multi-parametric magnetic resonance imaging at 3T. Computers in Biology and Medicine. 2018;99:154-160. |
| Choice A: | Differentiate tumor with hemorrhage, infection, edema, or micro-infiltration |
| Choice B: | Treatment assessment |
| Choice C: | Generate synthetic CT |
| Choice D: | Real-time treatment monitoring |
