Question 1: Which sequence used in DCE-MRI to detect enhancement in tissue signal intensity? |
Reference: | Reference: d'Arcy JA, et al., Informatics in Radiology (infoRAD): Magnetic Resonance Imaging Workbench: analysis and visualization of dynamic contrast-enhanced MR imaging data, RadioGraphics, 26:621-632, (2006) |
Choice A: | Proton-density sequence |
Choice B: | T1-weighted sequence |
Choice C: | T2*-weighted sequence |
Choice D: | Inversion recovery sequence |
Question 2: Eddy-current-induced distortions mostly affect the DWIs, but not significantly the b = 0 s/mm2 images. |
Reference: | Reference: Irfanoglu MO, Sarlls J, Nayak A, Pierpaoli C, Evaluating corrections for Eddy-currents and other EPI distortions in diffusion MRI: methodology and a dataset for benchmarking, Magn Reson Med., 81(4):2774-2787(2019);. doi: 10.1002/mrm.27577. |
Choice A: | True |
Choice B: | False |
Question 3: As the most popular image modality to detect tumor metabolic activity, FDG-PET/CT imaging feedback could be utilized to directly track spatial & temporal variation of tumor. |
Reference: | Reference: Boroughs LK & DeBerardinis RJ: Metabolic pathways promoting cancer cell survival and growth. Nature Cell Biology 2015, Vol 17:351-9 |
Choice A: | hypoxia |
Choice B: | proliferation |
Choice C: | intrinsic radiosensitivity |
Choice D: | survival and growth |
Question 4: Spatial variation of tumor voxel dose response assessed using multiple FDG-PET imaging can be managed adaptively by prescribed treatment dose to |
Reference: | Reference: Bentzen SM & Gregoire V: Molecular imaging-based dose painting: a novel paradigm for radiation therapy prescription. Semin Radiat Oncol 2011, Vol21101-10 |
Choice A: | each individual tumor |
Choice B: | individual tumor voxel |
Choice C: | all of the above |
Question 5: Advantages of PET/MR over PET/CT include all the following EXCEPT: |
Reference: | Reference: Habib Zaidi and Minerva Becker, The promise of hybrid PET/MRI: Technical advances and clinical applications. IEEE Signal Processing Magazine, 2016. 33(3): p. 67-85. |
Choice A: | reduced dose |
Choice B: | improved clinical management |
Choice C: | improved soft tissue contrast |
Choice D: | reduced technical and clinical workflow challenges |
Question 6: Based on recent studies, which of the following is recommended when interpreting conflicting data between PET and MRI metrics for response assessment (e.g. tumor size changes suggest recurrence, SUV indicates stable disease, perfusion MRI indicates stable disease, and diffusion changes suggest recurrence). |
Reference: | Reference: Habib Zaidi and Minerva Becker, The promise of hybrid PET/MRI: Technical advances and clinical applications. IEEE Signal Processing Magazine, 2016. 33(3): p. 67-85. |
Choice A: | Each imaging modality should be assigned a certain weight based on clinical experience |
Choice B: | Each disease site has their own recommendations |
Choice C: | There is no definitive recommendation |
Choice D: | Studies show that conflicting data between imaging modalities does not occur |