2020 Joint AAPM | COMP Virtual Meeting
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Session Title: Quantitative Imaging for Treatment Assessment
Question 1: Which sequence used in DCE-MRI to detect enhancement in tissue signal intensity?
Reference:Reference: d'Arcy JA, et al., Informatics in Radiology (infoRAD): Magnetic Resonance Imaging Workbench: analysis and visualization of dynamic contrast-enhanced MR imaging data, RadioGraphics, 26:621-632, (2006)
Choice A:Proton-density sequence
Choice B:T1-weighted sequence
Choice C:T2*-weighted sequence
Choice D:Inversion recovery sequence
Question 2: Eddy-current-induced distortions mostly affect the DWIs, but not significantly the b = 0 s/mm2 images.
Reference:Reference: Irfanoglu MO, Sarlls J, Nayak A, Pierpaoli C, Evaluating corrections for Eddy-currents and other EPI distortions in diffusion MRI: methodology and a dataset for benchmarking, Magn Reson Med., 81(4):2774-2787(2019);. doi: 10.1002/mrm.27577.
Choice A:True
Choice B:False
Question 3: As the most popular image modality to detect tumor metabolic activity, FDG-PET/CT imaging feedback could be utilized to directly track spatial & temporal variation of tumor.
Reference:Reference: Boroughs LK & DeBerardinis RJ: Metabolic pathways promoting cancer cell survival and growth. Nature Cell Biology 2015, Vol 17:351-9
Choice A:hypoxia
Choice B:proliferation
Choice C:intrinsic radiosensitivity
Choice D:survival and growth
Question 4: Spatial variation of tumor voxel dose response assessed using multiple FDG-PET imaging can be managed adaptively by prescribed treatment dose to
Reference:Reference: Bentzen SM & Gregoire V: Molecular imaging-based dose painting: a novel paradigm for radiation therapy prescription. Semin Radiat Oncol 2011, Vol21101-10
Choice A:each individual tumor
Choice B:individual tumor voxel
Choice C:all of the above
Question 5: Advantages of PET/MR over PET/CT include all the following EXCEPT:
Reference:Reference: Habib Zaidi and Minerva Becker, The promise of hybrid PET/MRI: Technical advances and clinical applications. IEEE Signal Processing Magazine, 2016. 33(3): p. 67-85.
Choice A:reduced dose
Choice B:improved clinical management
Choice C:improved soft tissue contrast
Choice D:reduced technical and clinical workflow challenges
Question 6: Based on recent studies, which of the following is recommended when interpreting conflicting data between PET and MRI metrics for response assessment (e.g. tumor size changes suggest recurrence, SUV indicates stable disease, perfusion MRI indicates stable disease, and diffusion changes suggest recurrence).
Reference:Reference: Habib Zaidi and Minerva Becker, The promise of hybrid PET/MRI: Technical advances and clinical applications. IEEE Signal Processing Magazine, 2016. 33(3): p. 67-85.
Choice A:Each imaging modality should be assigned a certain weight based on clinical experience
Choice B:Each disease site has their own recommendations
Choice C:There is no definitive recommendation
Choice D:Studies show that conflicting data between imaging modalities does not occur
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