2020 Joint AAPM | COMP Virtual Meeting
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Session Title: More than Just a Pretty Picture: Making MRI Quantitative
Question 1: Lee et al’s study of T1 relaxation time measurement in volunteers performed in two different vendor systems found:
Reference:Lee Y, Callaghan MF, Acost-Cabronero J, Lutti A, and Nagy Z, Establishing intra- and inter-vendor reproducibility of T1 relaxation time measurements with 3T MRI. Magnetic Resonance in Medicine 81:454-465 (2019).
Choice A:no difference between the two vendor systems.
Choice B:no change after software update.
Choice C:a bias between vendor systems.
Choice D:a bias between vendor systems and a greater bias with a software
Question 2: A quantitative MRI quality assurance program:
Reference:Friedman L and Glover GH, Report on a Multicenter fMRI Quality Assurance Protocol. Journal of Magnetic Resonance Imaging 23:827-839 (2006).
Choice A:is not necessary.
Choice B:can detect hardware problems that otherwise go undetected.
Choice C:can be completed annually with the ACR phantom quality assurance.
Question 3: Which of the following can be an error source which impacts the accuracy of qMRI?
Reference:Trzasko JD, Mostardi PM, Riederer SJ, Manduca A. Estimating T1 from multichannel variable flip angle SPGR sequences. Magn Reson Med. 2013;69(6):1787‐1794.
Choice A:Noise model
Choice B:Signal model
Choice C:Numerical fitting strategy
Choice D:All of the above
Question 4: Noise in a DICOM MR image is statistically distributed as:
Reference:Aja-Fernández, Santiago, and Gonzalo Vegas-Sánchez-Ferrero. "Statistical analysis of noise in MRI." Switzerland: Springer International Publishing (2016).
Choice A:Gaussian
Choice B:Rician
Choice C:The specific distribution varies and depends on many factors
Choice D:Not relevant to qMRI
Question 5: Of the MRI technique listed below, which one is most specific to brain tissue myelin content?
Reference:Heath F, Hurley SA, Johansen-Berg H, Sampaio-Baptista C. Advances in noninvasive myelin imaging. Developmental Neurobiology 2018; 78(2): 136-151.
Choice A:T1 relaxometry
Choice B:myelin water imaging
Choice C:T2* relaxometry
Choice D:T1-weighted/T2-weighted signal ratio
Question 6: Which of the following are challenges associated with cortical myelin mapping?
Reference:Waehnert MD, Dinse J, Schafer A, Geyer S, Bazin PL, Turner R, Tardif CL. A subject-specific framework for in vivo myeloarchitectonic analysis. NeuroImage 2016; 125: 94-107.
Choice A:lower myelin content in they grey matter in comparison to the white matter
Choice B:thin and convoluted shape of the cortex
Choice C:B1 field non-uniformity
Choice D:all of the above
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