Question 1: Which aspect of Image-Guided Small Animal Irradiators is most challenging in developing quality assurance tests? |
Reference: | Desrosiers M, DeWerd L, Deye J, Lindsay P, Murphy MK, Mitch M, Macchiarini F, Stojadinovic S, Stone H. The importance of dosimetry standardization in radiobiology. Journal of research of the National Institute of Standards and Technology. 2013;118:403. |
Choice A: | Energy dependence of most detectors at kV energies |
Choice B: | Inconsistent and inadequate access to physics training and equipment among operators |
Choice C: | Small field dosimetry and volume averaging effects |
Choice D: | High dose and high dose rate supra-linearity in detectors |
Question 2: Compared to other dosimeters, which of the following is not an advantage in the SARRP’s current EPID dosimetry for image-guided small animal irradiators? |
Reference: | Anvari A, Poirier Y, Sawant A. Development and implementation of EPID‐based quality assurance tests for the small animal radiation research platform (SARRP). Medical physics. 2018 Jul;45(7):3246-57. |
Choice A: | High spatial resolution |
Choice B: | Real-time signal acquisition |
Choice C: | Energy independence |
Choice D: | Measurement reproducibility and linearity |
Question 3: What is not a feature of the sparse orthogonal collimator? |
Reference: | Woods K, Nguyen D, Neph R, Ruan D, O'Connor D, Sheng K. A sparse orthogonal collimator for small animal intensity‐modulated radiation therapy part I: Planning system development and commissioning. Medical Physics. 2019 Dec;46(12):5703-13. |
Choice A: | Double focused leaves |
Choice B: | The modulation resolution is not determined by the leaf width |
Choice C: | The leaves are miniaturized proportionally to the size of the mouse |
Choice D: | Direct aperture optimization |
Choice E: | Tongue-and-groove to reduce inter-leaf leakage |
Question 4: What is a typical use case for SOC-IMRT? |
Reference: | Woods K, Neph R, Nguyen D, Sheng K. A sparse orthogonal collimator for small animal intensity‐modulated radiation therapy. Part II: hardware development and commissioning. Medical Physics. 2019 Dec;46(12):5733-47. |
Choice A: | Simultaneous integrated boost of a brain tumor |
Choice B: | Total-body irradiation |
Choice C: | Total marrow irradiation |
Choice D: | Irradiation of xenograft tumors on the hind leg |
Choice E: | A and C |
Choice F: | B and D |
Question 5: Incidental cardiac irradiation in lung cancer patients, with the dose delivered to the base of the heart is associated with poor survival with a dose threshold at: |
Reference: | McWilliam A, Kennedy J, Hodgson C, Osorio EV, Faivre-Finn C, van Herk M. Radiation dose to heart base linked with poorer survival in lung cancer patients. European Journal of Cancer. 2017 Nov 1;85:106-13. |
Choice A: | 10 Gy |
Choice B: | 8.5 Gy |
Choice C: | 16 Gy |
Question 6: The radiotherapy dose parameters for a breast cancer patient cohort correlated with: |
Reference: | van den Bogaard VA, van Luijk P, Hummel YM, van der Meer P, Schuit E, Boerman LM, Maass SW, Nauta JF, Steggink LC, Gietema JA, de Bock GH. Cardiac Function After Radiation Therapy for Breast Cancer. International Journal of Radiation Oncology* Biology* Physics. 2019 Jun 1;104(2):392-400. |
Choice A: | Global Longitudinal Strain of the Left Ventricle |
Choice B: | Left Ventricle Ejection Fraction |
Choice C: | Left Ventricle Wall thickness |