2021 AAPM Virtual Summer School
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Session Title: Session 2.2: MR-Sim Special Issues
Question 1: Within the context of current technology, the fourth dimension of 4D-MRI refers to:
Reference:Reference: Stemkens B, Paulson ES, Tijssen RHN. Nuts and bolts of 4D-MRI for radiotherapy. Phys Med Biol. 2018 Oct 23;63(21):21TR01. doi: 10.1088/1361-6560/aae56d
Choice A:Time
Choice B:Respiratory phase
Choice C:Fraction number
Choice D:None of the above
Question 2: Advantages of 3D acquisition strategies over 2D acquisition strategies for generation of 4D-MRI include:
Reference:Stemkens B, Paulson ES, Tijssen RHN. Nuts and bolts of 4D-MRI for radiotherapy. Phys Med Biol. 2018 Oct 23;63(21):21TR01. doi: 10.1088/1361-6560/aae56d.
Choice A:Increased signal-to-noise ratio (SNR)
Choice B:Contrast flexibility
Choice C:Reconstruction speed
Choice D:Image orientation flexibility
Choice E:None of the above
Question 3: Challenges with use of external surrogates for retrospective re-binning in 4D-MRI include:
Reference:Stemkens B, Paulson ES, Tijssen RHN. Nuts and bolts of 4D-MRI for radiotherapy. Phys Med Biol. 2018 Oct 23;63(21):21TR01. doi: 10.1088/1361-6560/aae56d.
Choice A:Signal saturation
Choice B:Gain resetting
Choice C:Synchronization of start and end times with pulse sequence acquisition
Choice D:Loss of phase coherence with acquired k-space data
Choice E:All of the above
Question 4: Which of the following motions is best characterized by cine MRI?
Reference:Paulson ES, Tijssen RHN. “Motion Management.” MRI for Radiotherapy, edited by Liney G and van der Heide UA, Springer, 2019, 107-116.
Choice A:Slow, ultracyclic motion
Choice B:Periodic motion
Choice C:Fast, aperiodic motion
Choice D:All of the above
Choice E:None of the above
Question 5: What is the main advantage of the MR-only workflow for RT plan simulation?
Reference:K. Brock and L. Dawson. Point: Principles of Magnetic Resonance Imaging Integration in a Computed Tomography-based Radiotherapy Workflow
Choice A:Improved special resolution and accuracy
Choice B:Less radiation dose delivered to the patient
Choice C:Simplified workflow due to less contouring
Choice D:Consistent target and OARs delineation and reduced image processing errors
Question 6: Which statement is correct with regard to MR-only and synthetic CT based simulation
Reference:J. Edmund and T. Nyholm. Counterpoint: A Review of Substitute CT Generation for MRI-only Radiation Therapy. Rad Oncol 12:28, 2017
Choice A:Synthetic CT requires a CT in addition to MR data
Choice B:MR-only workflows do not require any CT-related prior information
Choice C:Synthetic CT is used for both soft-tissue contouring and dose computations
Choice D:Synthetic CT is a desirable addition to the MR-only workflow to facilitate accurate dose computations
Question 7: Which of the following does NOT represent a method for facilitating the assignation of Hounsfield Units to MR data?
Reference:T. Nyholm and J. Jonsson. Opportunities and Challenges of a Magnetic Resonance Imaging–Only Radiotherapy Work Flow. Sem Rad Onc 175-180, 2014.
Choice A:Atlas-based segmentation
Choice B:Simulated annealing
Choice C:Manual contouring
Choice D:Voxelwise conversion
Question 8: Physician requested in the simulation order a field of view from the hip down to the knee for a large soft tissue sarcoma lesion. What is the best way to achieve the necessary field of view?
Reference:Paulson ES, Erickson B, Schultz C, Li XA. Comprehensive MRI simulation methodology using a dedicated MRI scanner in radiation oncology for external beam radiation treatment planning. Medical Physics. 2015;42(1):28-39.
Choice A:Increase slice thickness and in-plane pixel size to scan within reasonable time frame
Choice B:Angulate your planning scan volume for higher efficiency
Choice C:Step-and-shoot or continuous moving table acquisition
Choice D:Increase readout bandwidth
Question 9: For a prostate cancer patient with hip implants, which of the following strategies would aid with reducing metallic imaging artifacts?
Reference:Hargreaves BA, Worters PW, Pauly KB, Pauly JM, Koch KM, Gold GE. Metal-induced artifacts in MRI. AJR Am J Roentgenol. 2011;197(3):547-555. Lu W, Pauly KB, Gold GE, Pauly JM, Hargreaves BA. SEMAC: Slice Encoding for Metal Artifact Correction in MRI. Magnetic Resonance in Medicine. 2009;62(1):66-76
Choice A:Slice-encoding metal artifact correction (SEMAC)
Choice B:Use spin-echo based pulse sequence over GRE sequences
Choice C:View angle tilting (VAT)
Choice D:Increase receiver and excitation bandwidth
Choice E:All of the above
Question 10: Which of the following descriptions about MRI respiratory management methods are incorrect?
Reference:Glide-Hurst C, Paulson E, McGee K, Tyagi N, Hu Y, Balter J, Bayouth J. AAPM Task Group 284 Report: Magnetic Resonance Imaging Simulation in Radiotherapy: Considerations for Clinical Implementation, Optimization, and Quality Assurance. Medical Physics 2021
Choice A:Breath-hold imaging typically uses fast spin-echo sequences with parallel imaging and reduced phase resolution times
Choice B:Respiratory triggered acquisitions can be performed with internal MR navigators
Choice C:Desired respiratory phases can be acquired when the trigger level and trigger delay are optimized
Choice D:Cartesian sampling of k-space is more motion sensitive than Radial k-space sampling
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