| Question 1: In what wavelength range is the Cherenkov emission from patient during photon or electron radiation? |
| Reference: | 1) Yi Hong Ong; Andrew Q. Li; Timothy C. Zhu: Monte Carlo investigation of the
effect of skin tissue optical properties on detected Cherenkov emission. Proc SPIE 10862: 108621D March 2019 Notes: doi: 10.1117/12.2509854 |
| Choice A: | blue |
| Choice B: | yellow |
| Choice C: | red |
| Choice D: | all of the above |
| Question 2: The efficacy of photodynamic therapy depends on: |
| Reference: | Wang KK, Finlay JC, Busch TM, Hahn SM, and Zhu TC: Explicit dosimetry for photodynamic therapy: macroscopic singlet oxygen modeling, Journal of Biophotonics 3(5): 304-319, April 2010. |
| Choice A: | light fluence rate |
| Choice B: | light fluence |
| Choice C: | photosensitizer uptake |
| Choice D: | tissue oxygen |
| Choice E: | all of the above |
| Question 3: What strategy for accelerating iterative reconstruction has found success in both medical tomography and multiview microscopy? |
| Reference: | M. Guo, Y. Li, Y. Su, T. Lambert, D. D. Nogare, M. W. Moyle, L. H. Duncan, R. Ikegami, A. Santella, I. Rey-Suarez, D. Green, A. Beiriger, J. Chen, H. Vishwasrao, S. Ganesan, V. Prince, J. C. Waters, C. M. Annunziata, M. Hafner, W. A. Mohler, A. B. Chitnis, A. Upadhyaya, T. B. Usdin, Z. Bao, D. Colon-Ramos, P. La Riviere, H. Liu, Y. Wu, and H. Shroff, “Rapid image deconvolution and multiview fusion for optical microscopy,” Nature Biotechnology, 38(11):1337-1346, 2020, PMCID: PMC7642198.
Zeng, G. L. & Gullberg, G. T. Unmatched projector/backprojector pairs in an iterative reconstruction algorithm. IEEE Trans. Med. Imaging 19, 548–555 (2000). |
| Choice A: | unmatched backprojectors |
| Choice B: | random backprojectors |
| Choice C: | naked backprojectors |
| Choice D: | double backprojectors |
| Question 4: What acquisition scheme from optical microscopy has been recently adapted to x-ray florescence and luminescence imaging? |
| Reference: | 1) Quigley, B., Smith, C., Cheng, S.-H., Souris, J., Pelizzari, C., Chen, C.-T., Lo, L.-W., Reft, C., Wiersma, R., La Riviere, P. J. “Sensitivity evaluation and selective plane imaging geometry for x-ray-induced luminescence imaging,” Med Phys. 44(10):5367-5377 (2017). PMCID: PMC5646227.
Brůža P, Lin H, Vinogradov SA, Jarvis LA, Gladstone DJ, Pogue BW. Light sheet luminescence imaging with Cherenkov excitation in thick scattering media. Opt Lett. 2016;41(13):2986–2989. doi: 10.1364/OL.41.002986. |
| Choice A: | two-photon imaging |
| Choice B: | selective plane or light sheet illumination |
| Choice C: | differential interference contrast |
| Choice D: | stimulated emission depletion |
| Question 5: What are some opportunities specific for new and early stage investigators at NIBIB? |
| Reference: | NIBIB-supported Centers for Biomedical Imaging and Bioengineering https://www.nibib.nih.gov/research-funding/featured-programs/ncbib/supported-centers |
| Choice A: | Trailblazer R21 award |
| Choice B: | Stephen I. Katz R01 Research Project Grant |
| Choice C: | Parent P01 grant |
| Choice D: | Parent R01 grant |
| Question 6: How/where can you find out existing NIBIB National Technology Centers and their technologies? And how to collaborate with them? |
| Reference: | NIBIB-supported Centers for Biomedical Imaging and Bioengineering https://www.nibib.nih.gov/research-funding/featured-programs/ncbib/supported-centers |
| Choice A: | Talking with experienced R01 PIs who use them |
| Choice B: | Research on Pubmed publications from them |
| Choice C: | Through the NIBIB website |
| Choice D: | through talking to an NIBIB program officer |
| Choice E: | all of the above |
