2021 AAPM Virtual 63rd Annual Meeting
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Session Title: Not for the Faint of Heart: Functional Radiosurgery
Question 1: The ROSE trial of open surgery vs radiosurgery for mesial temporal lobe epilepsy demonstrated:
Reference:Barbaro NM, Quigg M, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess CP, Yu W, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, Knowlton RC, Bagić A, Henry T, Kapoor S, McKhann G, Palade AE, Reuber M, Tecoma E. Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial. Epilepsia. 2018 Jun;59(6):1198-1207. doi: 10.1111/epi.14045. Epub 2018 Mar 30. PubMed PMID: 29600809.
Choice A:Superiority of radiosurgery vs open surgery in seizure-free outcomes at three years
Choice B:Improved verbal memory preservation in the radiosurgery arm vs open surgery
Choice C:A higher number of seizure free patients following open surgery vs radiosurgery
Choice D:Acute toxicity was greater in the radiosurgery arm as compared to open surgery
Choice E:Quality of life outcomes were strongly associated with preservation of verbal memory
Question 2: What is the reported rate of bothersome new facial sensory impairment following radiosurgery for trigeminal neuralgia?
Reference:Kondziolka D, Zorro O, Lobato-Polo J, Kano H, Flannery TJ, Flickinger JC, Lunsford LD. Gamma Knife stereotactic radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg. 2010 Apr;112(4):758-65. doi: 10.3171/2009.7.JNS09694. PubMed PMID: 19747055. Pollock BE, Phuong LK, Gorman DA, Foote RL, Stafford SL. Stereotactic radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg. 2002 Aug;97(2):347-53. PubMed PMID: 12186463.
Choice A:5%
Choice B:10%
Choice C:15%
Choice D:20%
Choice E:25%
Question 3: Which organ will be considered the most for the treatment planning of the trigeminal neuralgia?
Reference:Reference: Principles and practice of stereotactic radiosurgery, 2nd ed, Lawrence S. Chin; William F. Regine, editors, Springer New York, 2015, pp 52
Choice A:Optic chiasm
Choice B:Brainstem
Choice C:Cochlea
Choice D:CN VII
Question 4: For Linac-based radiosurgery, which statement about trigeminal neuralgia is the most correct?
Reference:Reference: Principles and practice of stereotactic radiosurgery, 2nd ed, Lawrence S. Chin; William F. Regine, editors, Springer New York, 2015, pp 121-134
Choice A:MRI alone simulation and planning is the common procedure
Choice B:Gadolinium contrast MRI sequence is required
Choice C:Beam shaping is accomplished by plugging
Choice D:A spherical dose distribution is achieved by using multiple couch angles.
Question 5: What is the targeted area of the brain for radiosurgery treatment for essential tremor?
Reference:Nirajan, A., Raju, S.S., Kooshkabadi, A., Monaco, E., Flickinger, J.C., Lunsford, L.D., “Stereotactic Radiosurgery of Essential Tremor: Retrospective Analysis of a 19-Year Experience”, Movement Disorders 32(5): 2017.
Choice A:Hippocampus
Choice B:Posterior aspect of the caudate
Choice C:Ventralis intermedius nucleus (thalamus)
Choice D:Substantia nigra (basal ganglia)
Question 6: In a retrospective study of Gamma Ventral Capsulotomy for Obsessive Compulsive Disorder conducted by the International Radiosurgery Research Foundation, the mean maximum dose was:
Reference:Gupta, A., Shepard, M., Xu, Z., Maiti, T., Martinez-Moreno, N., Silverman, J., Iorio-Morin, C., Martinez-Alvarez, R., Barnett, G., Mathieu, D., Borghei-Razavi, H., Kondziolka, D., Sheehan, J., “An International Radiosurgery Research Foundation Multicenter Retrospective Study of Gamma Ventral Capsulotomy for Obsessive Compulsive Disorder”, Neurosurgery 85(6), 2019.
Choice A:40 Gy
Choice B:75 Gy
Choice C:90 Gy
Choice D:135 Gy
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