Question 1: The ROSE trial of open surgery vs radiosurgery for mesial temporal lobe epilepsy demonstrated: |
Reference: | Barbaro NM, Quigg M, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer
KD, Cole AJ, Sneed PK, Hess CP, Yu W, Tripathi M, Heck CN, Miller JW, Garcia PA,
McEvoy A, Fountain NB, Salanova V, Knowlton RC, Bagić A, Henry T, Kapoor S,
McKhann G, Palade AE, Reuber M, Tecoma E. Radiosurgery versus open surgery for
mesial temporal lobe epilepsy: The randomized, controlled ROSE trial. Epilepsia.
2018 Jun;59(6):1198-1207. doi: 10.1111/epi.14045. Epub 2018 Mar 30. PubMed PMID:
29600809. |
Choice A: | Superiority of radiosurgery vs open surgery in seizure-free outcomes at three years |
Choice B: | Improved verbal memory preservation in the radiosurgery arm vs open surgery |
Choice C: | A higher number of seizure free patients following open surgery vs radiosurgery |
Choice D: | Acute toxicity was greater in the radiosurgery arm as compared to open surgery |
Choice E: | Quality of life outcomes were strongly associated with preservation of verbal memory |
Question 2: What is the reported rate of bothersome new facial sensory impairment following radiosurgery for trigeminal neuralgia? |
Reference: | Kondziolka D, Zorro O, Lobato-Polo J, Kano H, Flannery TJ, Flickinger JC,
Lunsford LD. Gamma Knife stereotactic radiosurgery for idiopathic trigeminal
neuralgia. J Neurosurg. 2010 Apr;112(4):758-65. doi: 10.3171/2009.7.JNS09694.
PubMed PMID: 19747055.
Pollock BE, Phuong LK, Gorman DA, Foote RL, Stafford SL. Stereotactic
radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg. 2002
Aug;97(2):347-53. PubMed PMID: 12186463. |
Choice A: | 5% |
Choice B: | 10% |
Choice C: | 15% |
Choice D: | 20% |
Choice E: | 25% |
Question 3: Which organ will be considered the most for the treatment planning of the trigeminal neuralgia? |
Reference: | Reference: Principles and practice of stereotactic radiosurgery, 2nd ed, Lawrence S. Chin; William F. Regine, editors, Springer New York, 2015, pp 52 |
Choice A: | Optic chiasm |
Choice B: | Brainstem |
Choice C: | Cochlea |
Choice D: | CN VII |
Question 4: For Linac-based radiosurgery, which statement about trigeminal neuralgia is the most correct? |
Reference: | Reference: Principles and practice of stereotactic radiosurgery, 2nd ed, Lawrence S. Chin; William F. Regine, editors, Springer New York, 2015, pp 121-134 |
Choice A: | MRI alone simulation and planning is the common procedure |
Choice B: | Gadolinium contrast MRI sequence is required |
Choice C: | Beam shaping is accomplished by plugging |
Choice D: | A spherical dose distribution is achieved by using multiple couch angles. |
Question 5: What is the targeted area of the brain for radiosurgery treatment for essential tremor? |
Reference: | Nirajan, A., Raju, S.S., Kooshkabadi, A., Monaco, E., Flickinger, J.C., Lunsford, L.D., “Stereotactic Radiosurgery of Essential Tremor: Retrospective Analysis of a 19-Year Experience”, Movement Disorders 32(5): 2017. |
Choice A: | Hippocampus |
Choice B: | Posterior aspect of the caudate |
Choice C: | Ventralis intermedius nucleus (thalamus) |
Choice D: | Substantia nigra (basal ganglia) |
Question 6: In a retrospective study of Gamma Ventral Capsulotomy for Obsessive Compulsive Disorder conducted by the International Radiosurgery Research Foundation, the mean maximum dose was: |
Reference: | Gupta, A., Shepard, M., Xu, Z., Maiti, T., Martinez-Moreno, N., Silverman, J., Iorio-Morin, C., Martinez-Alvarez, R., Barnett, G., Mathieu, D., Borghei-Razavi, H., Kondziolka, D., Sheehan, J., “An International Radiosurgery Research Foundation Multicenter Retrospective Study of Gamma Ventral Capsulotomy for Obsessive Compulsive Disorder”, Neurosurgery 85(6), 2019. |
Choice A: | 40 Gy |
Choice B: | 75 Gy |
Choice C: | 90 Gy |
Choice D: | 135 Gy |