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A Method to Vectorize the Dose Distribution, the Dose Volume Histogram

C Mayo

C Mayo1*, C Zankowski2, M Herman1, R Miller4, K Olivier1, J Suominen3, (1) Mayo Clinic, Rochester, MN, (2) Varian Medical Systems, Palo Alto, CA, (3) Varian Medical Systems Finland, Helsinki,

SU-E-T-487 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

A programmatic method to incorporate spatial information into a dose volume histogram (DVH) by adding vector data on the location of pixels in the dose array relative to structures in the plan to construct a vectorized dose distribution (VDD) is defined and demonstrated. With this data the DVH can be sub grouped according to a wide array of vector constraint sets, defining the spatial relationship of pixels to one or several structures to construct a vectorized DVH (VDVH) to reveal vector relationships of dose regions to structures.

Set theory models for construction of the VDD and VDVH are described and a dose-vector-histogram (DVctH) is introduced as a means of specifying the position, with respect to other structures, of focal dose features such as hot spots, distributed dose regions and conformality. Practical detail on a programmatic approach to implement the methods is provided. A set of tests utilizing phantom, prostate and SBRT lung image sets were carried out to demonstrate ability of VDVH and DVctH to reveal clinically relevant spatial detail in dose distributions.

The VDVH and DVctH enabled decomposing DVH curves to reveal the relative location of pixels contributing to dose points on the curve. The metrics enabled specificity in defining the location and magnitude of dose features relevant to treatment plan evaluation.

The VDD, VDVH and DVctH differ from other methods described in the literature as a result of using vector based constraints for each pixel, rather than focusing only on distance by construction of a set of shells around or within a structure and then subgrouping pixels in the overlap region. The method is an effective means to combine spatial information with DVH metrics and provides a practical means of specifying the location of dose features with respect other structures in the treatment plan.

Funding Support, Disclosures, and Conflict of Interest: Varian Medical Systems

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