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Verification of Monitor Unit Calculation for Lung Stereotactic Body Radiation Therapy Using a Secondary Independent Planning System

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Y Tsuruta

Y Tsuruta1*, M Nakamura2 , M Nakata1 , Y Miyabe2 , M Akimoto2 , T Ono2 , N Mukumoto2 , Y Ishihara2 , Y Matsuo2 , K Higashimura1 ,T Mizowaki2 , M Hiraoka2 , (1) Kyoto University Hospital, Kyoto, Kyoto, (2) Kyoto University, Graduate School of Medicine, Kyoto


SU-E-T-351 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Purpose: To compare isocenter (IC) dose between X-ray Voxel Monte Carlo (XVMC) and Acuros XB (AXB) as part of an independent verification of monitor unit (MU) calculation for lung stereotactic body radiation therapy (SBRT) using a secondary independent treatment planning system (TPS).

Methods: Treatment plans of 110 lesions from 101 patients who underwent lung SBRT with Vero4DRT (Mitsubishi Heavy Industries, Ltd., Japan, and BrainLAB, Feldkirchen, Germany) were evaluated retrospectively. Dose distribution was calculated with X-ray Voxel Monte Carlo (XVMC) in iPlan 4.5.1 (BrainLAB, Feldkirchen, Germany) on averaged intensity projection images. A spatial resolution and mean variance were 2 mm and 2%, respectively. The clinical treatment plans were transferred from iPlan to Eclipse (Varian Medical Systems, Palo Alto, CA, USA), and doses were recalculated with well commissioned AXB ver. 11.0.31 while maintaining the XVMC-calculated MUs and beam arrangement. Dose calculations were made in the dose-to-medium dose reporting mode with the calculation grid size of 2.5 mm. The mean and standard deviation (SD) of the IC dose difference between XVMC and AXB were calculated. The tolerance level was defined as |mean|+2SD. Additionally, the relationship between IC dose difference and the size of planning target volume (PTV) or computed tomography (CT) value of internal target volume (ITV) was evaluated.

Results: The mean±SD of the IC dose difference between XVMC and AXB was -0.32±0.73%. The tolerance level was 1.8%. Absolute IC dose differences exceeding the tolerance level were observed in 3 patients (2.8%). There were no strong correlations between IC dose difference and PTV size (R=-0.14) or CT value of ITV (R=-0.33).

Conclusion: The present study suggested that independent verification of MU calculation for lung SBRT using a secondary TPS is useful.

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