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Dosimetric Effect of Rotational Errors for Lung Stereotactic Body Radiotherapy


J Lee

J Lee1*, J Park2, J Kim2, H Kim1, H Kim2,3 , S Ye1,2 , (1) Seoul National University Graduate School of Convergence Science and Technology, Seoul, (2) Seoul National University Hospital, Seoul, (3) Seoul National University College of Medicine, Seoul

Presentations

TH-A-9A-3 Thursday 7:30AM - 9:30AM Room: 9A

Purpose: To evaluate the dosimetric effects on target volume and organs at risk (OARs) due to roll rotational errors in treatment setup of stereotactic body radiation therapy (SBRT) for lung cancer.

Methods: There were a total of 23 volumetric modulated arc therapy (VMAT) plans for lung SBRT examined in this retrospective study. Each CT image of VMAT plans was intentionally rotated by ±1°, ±2°, and ±3° to simulate roll rotational setup errors. The axis of rotation was set at the center of T-spine. The target volume and OARs in the rotated CT images were re-defined by deformable registration of original contours. The dose distributions on each set of rotated images were re-calculated to cover the planning target volume (PTV) with the prescription dose before and after the couch translational correction. The dose-volumetric changes of PTVs and spinal cords were analyzed.

Results: The differences in D95% of PTVs by -3°, -2°, -1°, 1°, 2°, and 3° roll rotations before the couch translational correction were on average -11.3±11.4%, -5.46±7.24%, -1.11±1.38% -3.34±3.97%, -9.64±10.3%, and -16.3±14.7%, respectively. After the couch translational correction, those values were -0.195±0.544%, -0.159±0.391%, -0.188±0.262%, -0.310±0.270%, -0.407±0.331%, and -0.433±0.401%, respectively. The maximum dose difference of spinal cord among the 23 plans even after the couch translational correction was 25.9% at -3° rotation.

Conclusions: Roll rotational setup errors in lung SBRT significantly influenced the coverage of target volume using VMAT technique. This could be in part compensated by the translational couch correction. However, in spite of the translational correction, the delivered doses to the spinal cord could be more than the calculated doses. Therefore if rotational setup errors exist during lung SBRT using VMAT technique, the rotational correction would rather be considered to prevent over-irradiation of normal tissues than the translational correction.


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