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Beam Modeling and Validation with Triple and Double Gaussian Dose Kernel for Spot Scanning Proton Beams

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S Hirayama

S Hirayama1*, T Takayanagi1 , Y Fujii1 , R Fujimoto1 , S Fujitaka1 , M Umezawa1 , Y Nagamine2 , M Hosaka2 , K Yasui3 , T Toshito3 , (1) Hitachi, Ltd., Hitachi Research Laboratory, Hitachi-shi, Ibaraki-ken, (2) Hitachi, Ltd., Hitachi Works, Hitachi-shi, Ibaraki, (3) Nagoya Proton Therapy Center, Nagoya City West Medical Center, Nagoya-shi, Aichi,


TH-C-BRD-4 Thursday 10:15AM - 12:15PM Room: Ballroom D

Purpose:To present the validity of our beam modeling with double and triple Gaussian dose kernels for spot scanning proton beams in Nagoya Proton Therapy Center. This study investigates the conformance between the measurements and calculation results in absolute dose with two types of beam kernel.

Methods:A dose kernel is one of the important input data required for the treatment planning software. The dose kernel is the 3D dose distribution of an infinitesimal pencil beam of protons in water and consists of integral depth doses and lateral distributions. We have adopted double and triple Gaussian model as lateral distribution in order to take account of the large angle scattering due to nuclear reaction by fitting simulated in-water lateral dose profile for needle proton beam at various depths. The fitted parameters were interpolated as a function of depth in water and were stored as a separate look-up table for the each beam energy. The process of beam modeling is based on the method of MDACC [X.R.Zhu 2013].

Results:From the comparison results between the absolute doses calculated by double Gaussian model and those measured at the center of SOBP, the difference is increased up to 3.5% in the high-energy region because the large angle scattering due to nuclear reaction is not sufficiently considered at intermediate depths in the double Gaussian model. In case of employing triple Gaussian dose kernels, the measured absolute dose at the center of SOBP agrees with calculation wit±hin ±1% regardless of the SOBP width and maximum range.

Conclusion:We have demonstrated the beam modeling results of dose distribution employing double and triple Gaussian dose kernel. Treatment planning system with the triple Gaussian dose kernel has been successfully verified and applied to the patient treatment with a spot scanning technique in Nagoya Proton Therapy Center.

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