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From Dicom-RT to Radiobiological Dose Metrics in 5 Minutes

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B Whelan

B Whelan1,2*, L Holloway2,3 , (1) University of Sydney, Camperdown, NSW, (2) Ingahm Institute, Liverpool, AUS, (3) Liverpool Cancer Therapy Centre, Sydney, NSW


SU-E-T-194 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Purpose: To develop a flexible and standalone framework for batch calculation of radiobiological dose metrics from Dicom-RT.

Methods: Software has been developed which allows (1) The calculation of DVH data from DICOM dose and structure files (DVHgenerator), (2) Calculation of a wide range of radiobiological metrics from this data (CompPlanGui). Both these tools are run via graphical user interface (GUI), making them fast and simple. Part 1 is a new tool which has not previously been published, whilst part 2 is a GUI overlay for the previously published software 'Comp-Plan' (Holloway et. al., Medical Dosimetry, 2012), previously reliant on command line interface. The time taken for an experienced user to evaluate a test case of 6 plans with and without CompPlanGUI was quantified.

Results: The DVH-generator has been found to be faster, more robust and require far less physical memory then using alternative software solutions for the same purpose.
The Comp Plan GUI significantly reduces the amount of time required to set up a base directory, eliminates code crashes arising from typographical errors, and renders the code far more accessible to non-expert users. It took an experienced user of the code around 3 minutes to set up a base directory of 6 plans compared around 8 minutes without, indicating that using CompPlanGUI reduced setup time by over 50%.

Conclusion: A standalone GUI based framework has developed which allows for the batch calculation of radiobiological dose metrics directly from Dicom-RT files. As with the original code, this work will be made freely available on request, as well as via matlab file exchange.

Funding Support, Disclosures, and Conflict of Interest: We would like to thank Cancer Institute NSW for scholarship support.

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