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Program Information

Real-Time Catheter Localization Using An Active MR Tracker for Interstitial Brachytherapy

W Wang

W Wang1,2*, A Damato1,2 , T Penzkofer3 , L Pan4 , W Gilson4 , R Seethamraju5 , E Schmidt3 , A Viswanathan1,2 , R Cormack1,2 , (1) Dana Farber Cancer Institute / Brigham and Women's Hospital, Boston, MA, (2) Harvard Medical School, Boston, MA, (3) Brigham and Women's Hospital, Boston, MA, (4) Siemens Corporation, Corporate Technology, Baltimore, MD (6) Siemens Healthcare, Boston, MA


WE-G-17A-5 Wednesday 4:30PM - 6:00PM Room: 17A

To develop a novel active MR-tracking system which can provide accurate and rapid localization of brachytherapy catheters, and assess its reliability and spatial accuracy in comparison to standard catheter digitization using MR images.

An active MR tracker for brachytherapy was constructed by adding three printed-circuit micro-coils to the shaft of a commercial metallic stylet. A gel phantom with an embedded framework was built, into which fifteen 14-Gauge catheters were placed, following either with parallel or crossed paths. The tracker was inserted sequentially into each catheter, with MR-tracking running continuously. Tracking was also performed during the tracker’s removal from each catheter. Catheter trajectories measured from the insertion and the removal procedures using the same micro-coil were compared, as well as trajectories obtained using different micro-coils. A 3D high-resolution MR image dataset of the phantom was acquired and imported into a treatment planning system (TPS) for catheter digitization. A comparison between MR-tracked positions and positions digitized from MR images by TPS was performed.

The MR tracking shows good consistency for varying catheter paths and for all micro-coils (mean difference ~1.1 mm). The average distance between the MR-tracking trajectory and catheter digitization from the MR images was 1.1 mm. Ambiguity in catheter assignment from images due to crossed paths was resolved by active tracking. When tracking was interleaved with imaging, real-time images were continuously acquired at the instantaneous tip positions and displayed on an external workstation.

The active MR tracker may be used to provide an independent measurement of catheter location in the MR environment, potentially eliminating the need for subsequent CT. It may also be used to control real-time imaging of catheter placement. This will enable MR-based brachytherapy planning of interstitial implants without ionizing radiation, with the potential to enable dosimetric guidance of catheter placement.

Funding Support, Disclosures, and Conflict of Interest: We gratefully acknowledge support from the American Heart Association SDG 10SDG2610139, NIH 1R21CA158987-01A1, U41-RR019703, and R21 CA 167800, as well as a BWH Department of Radiation Oncology post-doctoral fellowship support. Li Pan and Wesley Gilson are employees of Siemens Corporation, Corporate Technology. Ravi Seethamraju is an employee of Siemens Healthcare.

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