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Scan Angle Reduction for a Limited-Angle Intrafraction Verification (LIVE) System

L Ren

L Ren*, Y Zhang , F Yin , Duke University Medical Center, Durham, NC


SU-E-I-56 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Purpose: To develop a novel adaptive reconstruction strategy to further reduce the scanning angle required by the limited-angle intrafraction verification (LIVE) system for intrafraction verification.

Methods: LIVE acquires limited angle MV projections from the exit fluence of the arc treatment beam or during gantry rotation between static beams. Orthogonal limited-angle kV projections are also acquired simultaneously to provide additional information. LIVE considers the on-board 4D-CBCT images as a deformation of the prior 4D-CT images, and solves the deformation field based on deformation models and data fidelity constraint. LIVE reaches a checkpoint after a limited-angle scan, and reconstructs 4D-CBCT for intrafraction verification at the checkpoint. In adaptive reconstruction strategy, a larger scanning angle of 30⁰ is used for the first checkpoint, and smaller scanning angles of 15⁰ are used for subsequent checkpoints. The on-board images reconstructed at the previous adjacent checkpoint are used as the prior images for reconstruction at the current checkpoint. As the algorithm only needs to reconstruct the small deformation occurred between adjacent checkpoints, projections from a smaller scan angle provide enough information for the reconstruction. XCAT was used to simulate tumor motion baseline drift of 2mm along sup-inf direction at every subsequent checkpoint, which are 15⁰ apart. Adaptive reconstruction strategy was used to reconstruct the images at each checkpoint using orthogonal 15⁰ kV and MV projections.

Results: Results showed that LIVE reconstructed the tumor volumes accurately using orthogonal 15⁰ kV-MV projections. Volume percentage differences (VPDs) were within 5% and center of mass shifts (COMS) were within 1mm for reconstruction at all checkpoints.

Conclusion: It’s feasible to use an adaptive reconstruction strategy to further reduce the scan angle needed by LIVE to allow faster and more frequent intrafraction verification to minimize the treatment errors in lung cancer treatments.

Funding Support, Disclosures, and Conflict of Interest: Grant from Varian Medical System

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