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Evaluation of Mobius Dose Calculation Engine Using Out of the Box Preconfigured Beam Data

R Cardan

R Cardan1*, A Faught2 , M Huang3 , S Benhabib4 , I Brezovich5 , D Followill6 , R Popple7 , (1) UAB University of Alabama, Birmingham, Birmingham, AL, (2) MD Anderson Cancer Center, Houston, TX, (3) University of Alabama at Birmingham, Birmingham, AL, (4) University of Alabama at Birmingham, Birmingham, AL, (5) Univ Alabama Birmingham, Birmingham, AL, (6) UT MD Anderson Cancer Center, Houston, TX, (7) Univ Alabama Birmingham, Birmingham, AL


SU-E-T-167 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Determine the dose calculation accuracy of a preconfigured Mobius server for use in secondary checks of a treatment planning system.

10 plans were created for irradiation on two of the IROC (formerly RPC) accreditation phantoms: 4 for the head and neck phantom and 6 for the lung phantom. The plans each were created using one of four different photon energies (6FFF, 10 FFF, 6X, and 15X) and were varied in treatment type including VMAT, step and shoot IMRT, dynamic MLC IMRT (DMLC), and conformal RT (CRT). The TLDs in the phantoms were contoured, and each plan was sent for calculation to Mobius software (Mobius Medical Systems, Houston, TX) with a default configuration. Each plan was then irradiated on the planned phantom 3 times to create an average reading across 56 TLDs. These readings were then compared against the corresponding Mobius calculation at each TLD location.

The mean difference (MD) normalized to the plan prescription dose between each TLD and Mobius calculation for all measurements was 0.5 ± 3.3%, with a maximum difference of 8.4%. The MD was 0.6 ± 3.8%, -2.0 ± 1.9%, 1.7 ± 3.7%, and 1.9 ± 1.2% across the 6FFF, 10FFF, 6X and 15X energies respectively. The MD was -1.2 ± 2.3% for lung plans and 1.8 ± 3.5% for head/neck plans. Across treatment types, the MD ranged from -1.8 ± 1.7% for CRT to 4.3 ± 2.4 % for DMLC.

Out of the box and preconfigured, Mobius provides accurate dose calculations with respect to beam energy, treatment type, and treatment site.

Funding Support, Disclosures, and Conflict of Interest: Work supported by PHS grant CA10953 and CA81647 (NCI, DHHS).

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