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Beam Performance of the Radiance 330 Proton Therapy System

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H Nazaryan

H Nazaryan1*, V Nazaryan1 , J Flanz2 , V Alexandrov3 , F Wang1 , (1) ProTom International, Inc., Flower Mound, TX, (2) Massachusetts General Hospital, Boston, MA, (3) ZAO ProTom, Protvino, Moscow region


SU-E-T-470 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Purpose:The ProTom Radiance 330 proton radiotherapy system is a fully functional, compact proton radiotherapy system that provides advanced proton delivery capabilities. It supports three-dimensional beam scanning with energy and intensity modulation. A series of measurements have been conducted to characterize the beam performance of the first installation of the system at the McLaren Proton Therapy Center in Flint, Michigan. These measurements were part of the technical commissioning of the system. Select measurements and results are presented.

Methods:The Radiance 330 proton beam energy range is 70-250 MeV for treatment, and up to 330 MeV for proton tomography and radiography. Its 3-D scanning capability, together with a small beam emittance and momentum spread, provides a highly efficient beam delivery. During the technical commissioning, treatment plans were created to deliver uniform maps at various energies to perform Gamma Index analysis. EBT3 Gafchromic films were irradiated using the Planned irradiation maps. Bragg Peak chamber was used to test the dynamic range during a scan in one layer for high (250 MeV) and Low (70 MeV) energies. The maximum and minimum range, range adjustment and modulation, distal dose falloff (80%-20%), pencil beam spot size, spot placement accuracy were also measured. The accuracy testing included acquiring images, image registration, receiving correction vectors and applying the corrections to the robotic patient positioner.

Results:Gamma Index analysis of the Treatment Planning System (TPS) data vs. Measured data showed more than 90% of points within (3%, 3mm) for the maps created by the TPS. At Isocenter Beam Size (One sigma) < 3mm at highest energy (250 MeV) in air. Beam delivery was within 0.6 mm of the intended target at the entrance and the exit of the beam, through the phantom.

Conclusion:The Radiance 330 Beam Performance Measurements have confirmed that the system operates as designed with excellent clinical performance specifications.

Funding Support, Disclosures, and Conflict of Interest: Hovakim Nazaryan, Vahagn Nazaryan and Fuhua Wang are employees of ProTom International, Inc. who contributed to the development and completed the technical commissioning of the Radiance 330 proton therapy delivery system manufactured by ProTom International.

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