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Dosimetric Study of Two Rotational Intensity-Modulated Radiotherapy in Thoracic Esophageal Carcinoma

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R Zhang

R Zhang*, W Bai, X Fan, R Qiu, D Liu, Z Chi, C Han, Hebei Medical University Fourth Hospital, Shijiazhuang, Hebei

PO-BPC-Exhibit Hall-26 Saturday  Room: Exhibit Hall

Purpose:To compare and analyze the dosimetry characteristics of volumetric modulated arc therapy(VMAT) versus constant dose rate intensity modulated arc therapy(IMAT) in the treatment of thoracic esophageal carcinoma.

Methods:Eighteen patients with thoracic esophageal carcinoma ₍the upper,the middle and the lower thorax were 6 cases,respectively₎ were selected to design IMAT and VMAT treatment plans on Varian clinical 23IX conventional linear accelerator and Elekta Synergy™ new generation linac, respectively. Prescription dose of 60Gy in 30 fractions, planning objectives for PTV were at least 95% reached the prescription dose and V110 no more than 10% .The maximum dose of spinal-cord below 45 Gy and lung's V5 ≤ 55%,V20 ≤ 28%, V30 ≤ 18% were constrained. PTV and tissue dose volume parameters,machine MU, treatment time and γ pass rate were compared. Using SPSS 19.0 software paired T-test analysis two sets of data.

Results:IMAT group compared with VMAT group showing that PTV's CI increased by 4.6%; heart's V40, V45, V50; lung's V30 and treatment time were reduced by 11.1%, 11.3%, 8.4%; 5.6%; 38.1%, respectively. But spinal-cord's D2, V40; lung's V3, V5, V10, V15, V20; and MU were increased by 2.9%, 47.7%;7.1%, 8.3%, 7.8%,8.3%, 8.5%; 48.8%, respectively. While there were no significant differences between IMAT and VMAT in the average dose of PTV,CTV,GTV,heart,spinal-cord,lung and the γ₍± 3mm, ± 3%₎ pass rate and DTA₍± 3mm, ± 3%₎ ₍distance-to-agreement₎.

Conclusion:IMAT in the treatment of time and tissue of high dose irradiated area is less than that of VMAT;but machine MU and tissue of low dose irradiated area is higher than that of in VMAT. These two treatment methods can meet the clinical demand, can be selected according to the actual situation of the patient treatment.

Funding Support, Disclosures, and Conflict of Interest: The scientific research foundation of Hebei provincial health department (project number: 20130253)

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