Encrypted login | home

Program Information

Carbon Digitally Reconstructed Radiography (CDRR): A GPU Based Tool for Fast and Versatile Carbonimaging Simulation

no image available
M F Dias

M F Dias1,2*, J Seco2 , G Baroni1,3 , M Riboldi1,3 , (1)Dipartamento di Elettronica, Informazione e Bioingegneria - DEIB, Politecnico di Milano, Italy(2) Department of Radiation Oncology, Francis H. Burr Proton Therapy Center Massachusetts General Hospital (MGH), Boston, Massachusetts, USA (3) Bioengineering Unit, Centro Nazionale di Adroterapia Oncologica, Pavia 27100, Italy


SU-F-J-204 (Sunday, July 31, 2016) 3:00 PM - 6:00 PM Room: Exhibit Hall

Purpose: Research in carbon imaging has been growing over the past years, as a way to increase treatment accuracy and patient positioning in carbon therapy. The purpose of this tool is to allow a fast and flexible way to generate CDRR data without the need to use Monte Carlo (MC) simulations. It can also be used to predict future clinically measured data.

Methods: A python interface has been developed, which uses information from CT or 4DCT and the
treatment calibration curve to compute the Water Equivalent Path Length (WEPL) of carbon ions. A GPU based ray tracing algorithm computes the WEPL of each individual carbon traveling through the CT voxels. A multiple peak detection method to estimate high contrast margin positioning has been implemented (described elsewhere). MC simulations have been used to simulate carbons depth dose curves in order to simulate the response of a range detector.

Results: The tool allows the upload of CT or 4DCT images. The user has the possibility to select
phase/slice of interested as well as position, angle...). The WEPL is represented as a range detector which can be used to assess range dilution and multiple peak detection effects. The tool also provides knowledge of the minimum energy that should be considered for imaging purposes. The multiple peak detection method has been used in a lung tumor case, showing an accuracy of 1mm in determine the exact interface position.

Conclusion:The tool offers an easy and fast way to simulate carbon imaging data. It can be used for educational and for clinical purposes, allowing the user to test beam energies and angles before real acquisition. An analysis add-on is being developed, where the used will have the opportunity to select different reconstruction methods and detector types (range or energy).

Funding Support, Disclosures, and Conflict of Interest: Fundacao para a Ciencia e a Tecnologia (FCT), PhD Grant number SFRH/BD/85749/2012

Contact Email: