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A Novel Beam-Light View, Collimating Applicator for HDR Ocular Conjunctiva Brachytherapy-Treatments

S Koren

S Koren1*, J Kindler2 , A Guemnie Tafo3 , G Cohen4 , E Reich2 , (1) Ziv Medical Center, Safed, ISRAEL ,(2) Rabin Medical Center, Petach Tikva, ISRAEL, (3) Institute Gustave Roussy, Paris, FRANCE ,(4) Memorial Sloan-Kettering Cancer Center, New York, NY


SU-F-T-21 (Sunday, July 31, 2016) 3:00 PM - 6:00 PM Room: Exhibit Hall


We propose the use of a HDR X-ray source collimator to apply a conformal, relatively small, radiation suitable for a single fraction with short delivery time. In addition, this technique can be applied using a radioactive source.


We have built a stainless steel 1.5 mm thick applicator, to accommodate the needle applicator of the Intra-Beam X-ray source. Additional cavity is created in the applicator to allow the hosting/nesting/positioning of a LED diode. This LED is allowing a pre-irradiation beam marking on the tissue. The visible light emitted from the opening of the collimated applicator will delineate/verify the aperture of the kV beam to be applied, as well as serve as distance indicator and will assist in the determination of dose to be delivered.
For the evaluation of the collimated spatial dose distribution we have performed water tank measurements using (IBA Dosimetry) with a 0.4 cc ion chamber (IBA Dosimetry). We have scanned a two dimensional array with 1mm pitch in depth and 0.3 mm step size laterally.
Additional verifications were conducted using Gaf-Chromic film for PDD measurements and Optical Stimulated Luminescence Dosimetry (OSLD, Landauer inc.) for absolute dosimetry.


The collimated applicator enables a conformal irradiated cross-section of about 3 mm square at the applicator surface was used in this study. A 180 seconds of 50 kVp delivery yielded 29 Gy, 20.6 Gy and 14.5 Gy at 5, 10 and 15 mm depths respectively. These results are in good agreement with the needle applicator depth dose curve published data.


We have demonstrated the feasibility of focal HDR brachytherapy for conjunctival and ocular tumors, using the Intra-Beam needle applicator with in-house developed collimator. The delivery time was found to be several minutes- suitable for an intra-operative procedure and will allow dose fractionation deliveries.

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