Encrypted login | home

Program Information

Experimental Assessment of Noise and Spatial Resolution in Virtual Non-Contrast Dual-Energy CT Images Across Multiple Patient Sizes and CT Systems

J Montoya

J Montoya*, A Ferrero , L Yu , S Leng , C McCollough , Mayo Clinic, Rochester, MN


WE-FG-207B-9 (Wednesday, August 3, 2016) 1:45 PM - 3:45 PM Room: 207B

To investigate the noise and spatial resolution properties of virtual non-contrast (VNC) dual-energy CT images compared to true non-contrast (TNC) images across multiple patient sizes and CT systems.

Torso-shaped water phantoms with lateral widths of 25, 30, 35, 40 and 45 cm and a high resolution bar pattern phantom (Catphan CTP528) were scanned using 2nd and 3rd generation dual-source CT systems (Scanner A: Somatom Definition Flash, Scanner B: Somatom Force, Siemens Healthcare) in dual-energy scan mode with the same radiation dose for a given phantom size. Tube potentials of 80/Sn140 and 100/Sn140 on Scanner A and 80/Sn150, 90/Sn150 and 100/Sn150 on Scanner B were evaluated to examine the impact of spectral separation. Images were reconstructed using a medium sharp quantitative kernel (Qr40), 1.0-mm thickness, 1.0-mm interval and 20 cm field of view. Mixed images served as TNC images. VNC images were created using commercial software (Virtual Unenhanced, Syngo VIA Version VA30, Siemens Healthcare). The noise power spectrum (NPS), area under the NPS, peak frequency of the NPS and image noise were measured for every phantom size and tube potential combination in TNC and VNC images. Results were compared within and between CT systems.

Minimal shift in NPS peak frequencies was observed in VNC images compared to TNC for NPS having pronounced peaks. Image noise and area under the NPS were higher in VNC images compared to TNC images across all tube potentials and for scanner A compared to scanner B. Limiting spatial resolution was deemed to be identical between VNC and TNC images.

Quantitative assessment of image quality in VNC images demonstrated higher noise but equivalent spatial resolution compared to TNC images. Decreased noise was observed in the 3rd generation dual-source CT system for tube potential pairs having greater spectral separation.

Funding Support, Disclosures, and Conflict of Interest: Dr. McCollough receives research support from Siemens Healthcare

Contact Email: