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Quantitative Multi-Energy Computed Tomography: Imaging and Therapy Advancements

T Schmidt

X Duan

R Layman

T Schmidt1*, X Duan2*, R Layman3*, (1) Marquette University, Milwaukee, WI, (2) UT Southwestern Medical Center, Dallas, TX, (3) UT MD Anderson Cancer Center, Houston, TX


4:30 PM : MECT systems overview and quantitative opportunities - T Schmidt, Presenting Author
5:00 PM : MECT material quantification: iodine and beyond - X Duan, Presenting Author
5:30 PM : Quantitative MECT material suppression - R Layman, Presenting Author

WE-G-702-0 (Wednesday, August 2, 2017) 4:30 PM - 6:00 PM Room: 702

MECT Systems Overview and Quantitative Opportunities

The clinical use of Multi-Energy CT systems (also known as Spectral CT) is increasing, with numerous applications related to material differentiation and quantification. The method by which multi-energy CT data is acquired varies across vendor systems. This presentation will review and compare the different approaches for multi-energy acquisition, including dual-source, kV switching, multi-layer detector, and photon-counting detector. Properties of the acquired multi-energy data will be discussed, along with the types of images that can be reconstructed. The opportunities for quantification will be introduced.

MECT Material Quantification: Iodine and Beyond

Multi-energy CT pushes the quantification capability of CT imaging to a new height. Conventional CT imaging relies on CT numbers for material quantification, but the capabilities are limited because different materials may have the same CT number. Multi-energy CT provides material-specific quantification based on material decomposition, which greatly boosts the capability of CT imaging as a quantitative imaging modality. Multi-energy CT provides various tools and enhanced quantitative information to increase diagnostic performance. Some of the common images include iodine map, uric acid map and effective atomic number. Clinical research on material quantification using multi-energy CT is still a very active academic field, e.g., fat and iron quantification in liver and multi-contrast agents in a single scan. In this presentation, we will discuss commonly available quantification tools on multi-energy CT scanners and a review of recent advancements in the literatures, which will help the audience to better understand the physics behind the tools and implementation for clinical use.

Quantitative MECT Material Suppression

Material suppression in CT requires differentiation and identification of individual materials. This is challenging in conventional single energy CT because materials that have the different elemental composition can be represented with the same CT number. MECT offers the opportunity to differentiate and classify various materials by acquiring two specta at different energies. The attenuation of the materials will be different for each energy spectra that will enable differentiation and quantification of individual materials. This presentation will review the recent advancements in MECT for both imaging and therapy to provide material suppression (i.e. water or virtual non-contrast) and material decomposition (metal artifact).

Learning Objectives:
1. Learn and appreciate the different approaches to quantitative multi-enery CT.
2. Understand and learn how to implement quantitative multi-energy CT for various materials across multiple vendors
3. Learn various approaches to multi-energy CT for material suppression in imaging and therapy applications.


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