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Leaf Interdigitation Can Improve the Plan Quality for Multiple Isolate Targets NSCLC Sliding Window IMRT Plans in Monaco

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J Duan

Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong province


SU-I-GPD-T-383 (Sunday, July 30, 2017) 3:00 PM - 6:00 PM Room: Exhibit Hall

Purpose: The purpose of this study was to experimentally assess the dosimetric impact of leaf interdigitation for NSCLC sliding window IMRT (dMLC) plans in Monaco TPS.

Methods: 20 NSCLC patients (one to four isolate targets) previously treated were re-planned for dMLC with and without leaf interdigitation. Elekta synergy linear accelerator was used in this study. The treatment plans were evaluated on the following dosimetric variables: conformity index, homogeneity index and the normal lung sparing.

Results: For one isolate target, the plan quality was equivalent with and without leaf interdigitation (p>0.05). For multiple targets, leaf interdigitation could improve the conformity index obviously (p<0.05). Meanwhile, leaf interdigitation showed well sparing for the normal lung (p<0.05).

Conclusion: The study shows that leaf interdigitation can improve the plan quality for multiple isolate targets NSCLC dMLC plans in Monaco TPS.

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