Encrypted login | home

Program Information

Commissioning of the Fast Dose Calculator for Passive Scattering Proton Therapy at The University of Texas MD Anderson Cancer Center

no image available
A Adair

A Adair1*, P Yepes2 , U Titt3 , D Mirkovic4 , R Mohan5 , (1) Rice University, Houston, TX, (2) Rice University/The University of Texas M. D. Anderson Cancer, Houston, TX, (3) MD Anderson Cancer Center, Houston, TX, (4) U.T M.D. Anderson Cancer Center, Houston, TX, (5) UT MD Anderson Cancer Center, Houston, TX


TU-L-GePD-TT-1 (Tuesday, August 1, 2017) 1:15 PM - 1:45 PM Room: Therapy ePoster Theater

Purpose: To commission the Fast Dose Calculator (FDC), a Monte Carlo (MC) GEANT4-Based track repeating algorithm for passive scattering proton therapy (PSPT) at The University of Texas MD Anderson Cancer Center (MDACC).

Methods: The commissioning includes three general components: development of a patient independent PSPT beamline configuration (option) database for use as a beam source in FDC, assessing the validity of using of these options in FDC, and energy calibration of FDC with regards to measurement taken at the MDACC PSPT beamline. The options database is obtained through modeling of the MDACC PSPT beamline before the patient dependent components (downstream) with Monte Carlo N-Particle eXtended Code (MCNPX). The options take the form of phase-space files. Additionally, for a few patient dependent options a patient dependent MCNPX phase-space file is generated after the last patient dependent component (upstream). The validity of using MCNPX options with FDC is checked by assessing the gamma index of the energy deposition in a water phantom, between the downstream and upstream phase-space files in FDC. FDC energy calibration is done by assessing the gamma index of the energy deposition in a water phantom on a PSPT beamline with minimal components, between FDC and the corresponding measurements taken experimentally at MDACC.

Results: The FDC is commissioned for PSPT at MDACC.

Conclusion: The FDC allows for fast real-time simulation of intensity modulated proton therapy (IMPT) and PSPT. In the past, FDC has only been used in large scale for IMPT. FDC has been used as a tool for verification, retrospective analysis, and sometimes more accurate dose calculations. Through means of commissioning and the options database, FDC is now available to provide these same benefits for PSPT.

Funding Support, Disclosures, and Conflict of Interest: CPRIT GRANT

Contact Email: