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One-Scan Protocol: Verifying the Delivery of Spot-Scanning Proton Beam

M Chan

M Chan1*, C Chen2 , J Li1 , X Tang3 , X Li4 , G Tang5, D Mah2 , (1) Memorial Sloan-Kettering Cancer Center, Basking Ridge, NJ, (2) Procure Treatment Center, Somerset, NJ, (3) Memorial Sloan Kettering Cancer Center, West Harrison, NY, (4) Memorial Sloan Kettering Cancer Center, Rockville Centre, NY, (5) Memorial Sloan Kettering Cancer Center, New York, NY


SU-F-T-173 (Sunday, July 31, 2016) 3:00 PM - 6:00 PM Room: Exhibit Hall

Purpose: Radiochromic film for spot-scanning QA provides high spatial resolution and efficiency gains from one-shot irradiation for multiple depths. However, calibration can be a tedious procedure which may limit widespread use. Moreover, since there may be an energy dependence, which manifests as a depth dependence, this may require additional measurements for each patient. We present a one-scan protocol to simplify the procedure.

Methods: We performed the calibration using an EBT3 film at depths of 18, 20, 24cm of Plastic Water exposed by a 6-level step-wedge plan on a Proteus Plus proton system (IBA, Belgium). The calibration doses ranged 65-250 cGy(RBE) for proton energies of 170-200MeV. A clinical prostate+nodes plan was used for validation. The planar doses at selected depths were measured with EBT3 films and analyzed using one-scan protocol (one-scan digitization of QA film and at least one film exposed to known dose). The Gamma passing rates, dose-difference maps, and profiles of 2D planar doses measured with EBT3 film, IBA MatriXX PT, versus TPS calculations were analyzed and compared.

Results: The EBT3 film measurement results matched well with the TPS calculation data with an average passing rate of ~95% for 2%/2mm and slightly lower passing rates were obtained from an ion chamber array detector. We were able to demonstrate that the use of a proton step-wedge provided clinically acceptable results and minimized variations between film-scanner orientation, inter-scan, and scanning conditions. Furthermore, it could be derived from no more than two films exposed to known doses (one could be zero) for rescaling the master calibration curve at each depth.

Conclusion: The use of a proton step-wedge for calibration of EBT3 film increases efficiency. The sensitivity of the calibration to depth variations has been explored. One-scan protocol results appear to be comparable to that of the ion chamber array detector.

Funding Support, Disclosures, and Conflict of Interest: One author has a research grant from Ashland Inc., the manufacturer of the GafChromic film.

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