Program Information
The Feasibility of Using A Knowledge Base of Prior Treatment Plans in Cervical Cancer: A Dosimetric Comparision with Original Plans
C Ma*, Y Yin , Shandong Tumor Hospital, Jinan, Shandong Provice
Presentations
SU-E-T-735 (Sunday, July 12, 2015) 3:00 PM - 6:00 PM Room: Exhibit Hall
Purpose:
To demonstrate the feasibility of using a knowledge base of prior treatment plans to generate new cervical intensity modulated radiation therapy (IMRT) plans. Dosimetric diffeerences were investigated between knowledge-based IMRT rapidplans and original plans.
Methods:
A database of 20 cervical IMRT treatment plans were assembled to create a knowledge-based IMRT rapidplan model. Another 19 clinical cases were randomly selected to test the model. A comparision of the difference in the dose-volume histograms(DVH) between the semiautomated treatment plans and the original treatment plans were analyzed.
Results:
On average, the new knowledge-based rapidplans are capable of achieving very comparable planning target volume coverage as the original plan, to within 1% as evaluated for D98, D95, and D1. For the rectum, the mean and standard deviation of the dose percentage differences for D20, D30, and D50 are3.79%±8.31%, 4.00%±9.87%, and 1.52±10.89%, respectively. For the bladder, the mean and standard deviation of the dose percentage differences for D20, D30, and D50 are -2.43%±9.40%, -2.03%±10.17% and -2.94%±12.30%, respectively. For the femoral heads, the mean and standard deviation of the dose percentage differences for the left and right are 3.15%±18.29% and -3.18%±13.79%. A negative percentage difference indicates that the new plan has greater dose sparing as compared to the original plan.
Conclusion:
We demonstrate a knowledge-based IMRT model in cervical cancer can generate clinically acceptable treatment plans of high quality. This semiautomated approach can improve the efficiency of the treatment planning process while ensuring that high quality plans are developed.
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