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Image-Guided Patient-Specific Quality Assurance for Multi-Target Single Isocenter Intracranial VMAT Radiosurgery

M Huang

M Huang*, I Brezovich , J Duan , X Wu , S Shen , R. Cardan J Fiveash , R Popple , Univ Alabama Birmingham, Birmingham, AL


SU-E-T-453 (Sunday, July 12, 2015) 3:00 PM - 6:00 PM Room: Exhibit Hall

Purpose: To demonstrate a patient specific, image-guided quality assurance method that tests both dosimetric and geometric accuracy for single-isocenter multiple-target VMAT radiosurgery (SIMT-VMAT-SRS)

Method: We used a new film type, EBT-XD (optimal range 0.4-40Gy), and an in-house PMMA phantom having a coronal plane for film and a 0.125 cm3 ionization chamber (IC). The phantom contained fiducial features for kV image guided setup and for accurate film marking. Five patient plans with multiple targets sizes ranging from 3 to 21mm in diameter and prescribed doses from 14 to 18 Gy were selected. Two verification plans were generated for each case with the film plane passing through the center of the largest and smallest targets. For the four largest targets we obtained an IC measurement. For each case, a calibration film was irradiated using a custom designed step pattern . The films were scanned using a flatbed color scanner and converted to dose using the calibration film and the three channel calibration method. Image registration was performed between film and treatment planning system calculations to evaluate the geometric accuracy.

Results: The mean registration vector had an average magnitude of 0.47 mm (range from 0.13mm to 0.64 mm). For the four largest targets, the mean ratio of the IC and film measurement to expected dose was 0.990 (range 0.968 to 1.009) and 1.032 (1.021 to 1.046), respectively. The fraction of pixels having gamma index < 1 for criteria of 3%/3mm, 3%/2mm, 3%/1mm was 98.8%, 97.5% and 87.2% before geometric registration and 99.1%, 98.3% and 94.8% after registration.

Conclusion: We have demonstrated an image-guided QA method can assess both geometric and dosimetric accuracy. The phantom was positioned with sub-millimeter accuracy. Absolute film dosimetry using EBT-XD film was sufficiently accurate for assessment of dose to multi-targets too small for IC measurement in SRS VMAT plans.

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