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Assessment of MRI Geometric Distortion in Head and Neck Cancer Patients Scanned in Immobilized Radiation Treatment Position

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A Mohamed

C Hansen , A Mohamed*, J Weygand , Y Ding , C Fuller , S Frank , J Wang , MD Anderson Cancer Center, Houston, TX


SU-E-J-220 (Sunday, July 12, 2015) 3:00 PM - 6:00 PM Room: Exhibit Hall

Purpose: Uncertainties about geometric distortion have somewhat hindered MRI simulation in radiation therapy. Most of the geometric distortion studies were performed with phantom measurements but another major aspect of MR distortion is patient related. We studied the geometric distortion in patient images by comparing their MRI scans with the corresponding CT, using CT as the non-distorted gold standard.

Methods: Ten H&N cancer patients were imaged with MRI as part of a prospective IRB approved study. All patients had their treatment planning CT done on the same day or within one week of the MRI. MR Images were acquired with a T2 SE sequence (1x1x2.5mm voxel size) in the same immobilization position as in the CT scans. MRI to CT rigid registration was then done and geometric distortion comparison was done by measuring the corresponding anatomical landmarks on both the MRI and the CT images by two observers. Several skin to skin (9 landmarks), bone to bone (8 landmarks), and soft tissue (3 landmarks) were measured at specific levels in horizontal and vertical planes of both scans.

Results: The mean distortion for all landmark measurements in all scans was 1.8±1.9mm. For each patient 11 measurements were done in the horizontal plane while 9 were done in the vertical plane. The measured geometric distortion were significantly lower in the horizontal axis compared to the vertical axis (1.3±0.16 mm vs 2.2±0.19 mm, respectively, P=0.003*). The magnitude of distortion was lower in the bone to bone landmarks compared to the combined soft tissue and skin to skin landmarks (1.2±0.19 mm vs 2.3±0.17 mm, P=0.0006*). The mean distortion measured by observer one was not significantly different compared to
observer 2 (2.3 vs 2.4 mm, P=0.4).

Conclusion: MRI geometric distortions were quantified in H&N patients with mean error of less than 2 mm.

Funding Support, Disclosures, and Conflict of Interest: JW received a corporate sponsored research grant from Elekta

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