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Program Information

Nanoparticles for Imaging and Therapy

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S Krishnan

T Lammers

R Berbeco

S Krishnan1*, T Lammers2*, R Berbeco3*, (1) MD Anderson Cancer Center, Houston, TX, (2) University of Aachen, Aachen, DE, (3) Brigham and Women's Hospital, Boston, MA


10:00 AM : Nanoparticles in cancer medicine - a physician’s perspective - S Krishnan, Presenting Author
10:40 AM : Nanomedicine and theranostics - T Lammers, Presenting Author
11:20 AM : Nanoparticles from bench to MR-guided bedside - R Berbeco, Presenting Author

TH-CD-605-0 (Thursday, August 3, 2017) 10:00 AM - 12:00 PM Room: 605

Nanoparticle-based solutions are emerging for drug delivery, imaging and radiation dose amplification. Multi-functional platforms have been designed to deliver therapy and imaging agents preferentially to the site of disease. Challenges to clinical implementation include biodistribution, toxicity, targeting and scalable efficacy. In this session, we will present the current status of preclinical and clinical development of several of the most promising formulations. Topics addressed will include nanoparticle physics and pharmacology, as well as the interaction of nanoparticles with tumor biology and physiology.

Learning Objectives
1. Attendees will learn about factors that effect nanoparticle uptake and subsequent efficacy
2. Attendees will learn about optimizing nanoparticle design for clinical translation
3. Attendees will learn about the challenges of clinical translation of nanoparticles for imaging and therapy

Funding Support, Disclosures, and Conflict of Interest: NIH/NCI R01CA88446, NIH/NCI R21CA188833, Varian Medical Systems, Inc.


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