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Working Group on Biological Effects of Hypofractionated Radiotherapy/SBRT (WGSBRT)

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ChargeThe radiobiology of hypofractionated treatments may differ considerably from that of standard fractionated treatments, in regards to repair, reoxygenation, dose-rate effects, volume effects, fraction size effects, etc. The working group will generate reports, including but not limited to, critically surveying the published data regarding: 1. Tumor response: review of the effect of hypofractionation on local control. 2. Normal tissue response: review of the effect of hypofractionation on normal tissue tolerances. 3. Radiobiology of hypofractionated treatments. 4. Clinical rationales for the diverse prescription schemes in current use (e.g. 20GyX3 vs 24GyX1). 5. Standards for reporting outcome, including endpoints, defining/contouring of target and normal structures, dose definitions.
Bylaws:Not Referenced.Rules: Not Referenced.
Approved Date(s)n/a
Committee Keywords: WGSBRT

Jimm Grimm
Workgroup Chair

2019 Roster

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