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HyTEC 2105 - Tumor Control Probability of Radiosurgery and Fractionated Stereotactic Radiosurgery for Brain Metastases (2020)

Category: HyTEC

A pooled analysis of manuscripts evaluating tumor control probability for patients treated with stereotactic radiosurgery and fractionated stereotactic radiosurgery for brain metastases was performed. Studies reporting 1-year local control data for at least 10 patients were included in a tumor control probability model. Local control for tumors ≤2.0 cm in a single fraction was 85% for 18 Gy and 95% for 24 Gy. Fractionated regimens should be considered for larger tumors.

Supplemental Materials 1

International Journal of Radiation Oncology*Biology*Physics

Kristin J. Redmond, MD, Chengcheng Gui, BS, Stanley Benedict, PhD, Michael T. Milano, MD, Jimm Grimm, PhD, J. Austin Vargo, MD, Scott G. Soltys, MD, Ellen Yorke, PhD, Andrew Jackson, PhD, Issam El Naqa, PhD, Lawrence B. Marks, MD, Jinyu Xue, PhD, Dwight E. Heron, MD, MBA, and Lawrence R. Kleinberg, MD

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