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Calculation of Dose Distribution of Accuboost Brachytherapy in Deformable Polyvinil Alcohol Breast Phantom Using Biomechanical Modeling and Monte Carlo Simulation

p mohammadyari

p mohammadyari1*, r faghihi2 , m mosleh shirazi3 , m lotfi4 , A Meigooni5 , (1) Nuclear Engineering Department, School of Mechanical Engineering, Shiraz Un, Ilam, ilam, (2) Nuclear Engineering Department,Shiraz University, Shiraz, fars, (3) Radiotherapy & Oncology Department, Namazi Hospital, Shiraz University of M, Shiraz, fars, (4) Shiraz University of Medical Sciences, Medical Imaging Research Center, Shiraz, fars, (5) Comprehensive cancer center of Nevada - University of Nevada Las Vegas (UNL, Las Vegas, Nevada


SU-E-T-58 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Purpose:the accuboost is the most modern method of breast brachytherapy that is a boost method in compressed tissue by a mammography unit. the dose distribution in uncompressed tissue, as compressed tissue is important that should be characterized.

In this study, the mechanical behavior of breast in mammography loading, the displacement of breast tissue and the dose distribution in compressed and uncompressed tissue, are investigated. Dosimetry was performed by two dosimeter methods of Monte Carlo simulations using MCNP5 code and thermoluminescence dosimeters. For Monte Carlo simulations, the dose values in cubical lattice were calculated using tally F6. The displacement of the breast elements was simulated by Finite element model and calculated using ABAQUS software, from which the 3D dose distribution in uncompressed tissue was determined. The geometry of the model is constructed from MR images of 6 volunteers. Experimental dosimetery was performed by placing the thermoluminescence dosimeters into the polyvinyl alcohol breast equivalent phantom and on the proximal edge of compression plates to the chest.

The results indicate that using the cone applicators would deliver more than 95% of dose to the depth of 5 to 17mm, while round applicator will increase the skin dose. Nodal displacement, in presence of gravity and 60N forces, i.e. in mammography compression, was determined with 43% contraction in the loading direction and 37% expansion in orthogonal orientation. Finally, in comparison of the acquired from thermoluminescence dosimeters with MCNP5, they are consistent with each other in breast phantom and in chest's skin with average different percentage of 13.7±5.7 and 7.7±2.3, respectively.

The major advantage of this kind of dosimetry is the ability of 3D dose calculation by FE Modeling. Finally, polyvinyl alcohol is a reliable material as a breast tissue equivalent dosimetric phantom that provides the ability of TLD dosimetry for validation.

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