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Commissioning of the On-Board Cone-Beam CT System Equipped On the Rotating Gantry of a Proton Therapy System

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S Takao

S Takao1*, S Shimizu2 , N Miyamoto1 , T Matsuura1 , C Toramatsu1 , H Nihongi1 , T Yamada1 , K Matsuda3 , T Sasaki3 , Y Nagamine3 , R Baba4 , T Umekawa5 , K Umegaki1 , H Shirato2 , (1) Department of Medical Physics, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, (2) Department of Radiation Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, (3) Hitachi Works, Hitachi, Ltd., Hitachi, Ibaraki, (4) Central Research Laboratory, Hitachi, Ltd, Kokubunji, Tokyo, (5) Hitachi Research Laboratory, Hitachi, Ltd, Hitachi, Ibaraki


SU-E-CAMPUS-J-3 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Purpose: Proton therapy requires highly-precise image guidance in patient setup to ensure accurate dose delivery. Cone-beam CT (CBCT) is expected to play an important role to reduce uncertainties in patient setup. Hokkaido University has developed a new proton therapy system dedicated to spot-scanning under a collaborative work with Hitachi Ltd. In our system, an orthogonal X-ray imaging system is mounted on a full-rotating gantry. On-board CBCT imaging is therefore available. We have conducted commissioning of the CBCT system for clinical use in proton therapy.

Methods: The orthogonal X-ray imaging system, which consists of two sets of X-ray tubes and flat panel detectors (FPDs), are equipped on the rotating gantry. The FPDs are mounted on the proton beam nozzle and can be retracted when not in use. The distance between the X-ray source and the FPD is about 2.1 m. The maximum rotation speed of the gantry is 1 rpm, so CBCT images can be acquired in approximately 1 minute. The maximum reconstruction volume is nearly 40 cm in diameter and 20 cm in axial length. For commissioning of the CBCT system, mechanical accuracy of the rotating gantry first was evaluated. Imaging performance was examined via quantitative evaluation of image quality.

Results: Through the mechanical test, the isocentricity of the gantry was confirmed to be less than 1 mm. Moreover, it was improved to 0.5 mm with an appropriate correction. The accurate rotation of the gantry contributes to the CBCT image quality. In the image quality test, objects with 7 line-pairs per cm, which corresponds to a line spacing of 0.071 cm, could be discerned. Spatial linearity and uniformity were also sufficient.

Conclusion: Clinical commissioning of the on-board CBCT system for proton therapy was conducted, and CBCT images with sufficient quality were successfully obtained.

Funding Support, Disclosures, and Conflict of Interest: This research was supported by the Cabinet Office, Government of Japan and the Japan Society for the Promotion of Science (JSPS) through the Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program), initiated by the Council for Science and Technology Policy (CSTP).

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