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Differences in Applicator Configuration and Dwell Loading Between Standard and Image-Guided Tandem and Ring (T&R) HDR Brachytherapy

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A Damato

A Damato*, R Cormack , M Bhagwat , I Buzurovic , L Lee , A Viswanathan , Brigham and Women's Hospital, Boston, MA


WE-A-17A-5 Wednesday 7:30AM - 9:30AM Room: 17A

To investigate differences in: (i) relative location of the tandem and the ring compared to a rigid standard applicator model; and (ii) relative loading and changes in loading pattern between standard and image-guided planning.

All T&R insertions performed in 2013 in our institution under CT- or MR-guidance were analyzed. Standard plans were generated using library applicator models with a fixed relationship between ring and tandem, standardized uniform dwell loading and normalization to point A. The graphic plans and the associated standard-plan dwell configurations were compared: the rings were rigidly registered, and the residual tandem shift, rotation and maximum distance between plan tandem dwell and corresponding model tandem dwell were calculated. The normalization ratio (NR = the ratio of graphic versus standard-plan total reference air kerma [TRAK]), the general loading difference (GLD = the difference between graphic and standard ratios of the tandem versus the ring TRAK), and the percent standard deviation (SD% = SD/mean) of the tandem and the ring TRAK for the graphic plan (all standard-plans SD% = 0) were calculated.

71 T&R were analyzed. Residual tandem shift, rotation and maximum corresponding dwell distance were 1.2±0.8mm (0.4±0.4mm lateral, 0.9±0.8mm craniocaudal, 0.4±0.3mm anterior-posterior), 2.3±1.9deg and 3.4±2.3mm. NR was 0.86±0.11 indicating a lower overall loading of the graphic compared to the standard plans. GLD was -0.12±0.16 indicating a modest increased ring loading relative to the tandem in the graphic plans. SD% was 2.1±1.6% for tandem and 2.8±1.9% for ring, indicating small deviations from uniform loading.

Variability in the relative locations of the tandem and the ring necessitates the independent registration of each component model for accurate digitization. Our clinical experience suggests that graphically planned T&R results on average in a lower total dose to the patient, and in an increased relative loading of the ring component.

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