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Beam Characteristics and Treatment Planning Commissioning for a New Proton Therapy Unit

T Zhao

T Zhao*, B Sun , K Grantham , L Santanam , S Goddu , E Klein , Washington University, St. Louis, MO


SU-E-T-572 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Purpose:A single-room proton system, the Mevion S250, was introduced into the arena of proton radiotherapy by Mevion Medical Systems. The first unit was installed and operates at the S. Lee Kling Proton Therapy Center at Barnes-Jewish Hospital. The objective of this abstract is to report the system’s beam characteristics and Eclipse commissioning.

Methods:Commissioning data were acquired for modelling longitudinal fluence, virtual source position, effective source position, source size and Bragg peaks in Eclipse. Stoichiometric CT calibration was generated via ICRU44 human. Spread-out Bragg peaks (SOBP) were measured with Parallel Plate Chamber and profiles with solid state detector for model validation. Heterogeneity effects were measured with bone and lung inserts in the beam line. RT dose was computed in a virtual water phantom, and exported from Eclipse to compare with measurements at various depths and axis. SOBPs were fine-tuned with partial shining correction and entry correction to match measurements. Output factor was measured for each individual field with an ADCL ion chamber in a water tank and fitted to a polynomial function to cross-check the monitor unit verification.

Results:Ranges of all 24 options were measured within ±1mm tolerance. Modulations met a ±1mm or ±2% tolerance. SOBP flatness met a ±3% tolerance. Distal fall off (80%-20%) were measured between 6mm and 7mm for all options. Virtual source positions varied between 177cm and 195cm, decreasing with field size and range. SOBP generated by Eclipse agreed with measurements within ±3% in the entry region, and ±1%/±1mm in other regions. Sanity check for output achieved 5% accuracy in 98% of cases.

Conclusion:The commissioning of the first Mevions S250 proton therapy system met specifications. The unit has been put in clinical operation since 12/17/2013.

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